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dc.contributor.supervisor O, Karmin (Animal Science) en_US
dc.contributor.author Amarakoon, Amarakoon Mudiyanselage Sirini Buddhika Kumari
dc.date.accessioned 2017-09-07T16:00:18Z
dc.date.available 2017-09-07T16:00:18Z
dc.date.issued 2017
dc.identifier.uri http://hdl.handle.net/1993/32492
dc.description.abstract Oxidative stress is a deleterious process that causes various pathological processes in humans and animals. The objectives of this study were to investigate the changes in oxidative status in weaned piglets after an E. coli K88+ challenge and to determine the effects of dietary supplementation of red osier dogwoods plant products and epidermal growth factor (EGF) on oxidative stress in these piglets. TBARS and superoxide dismutase enzyme activity were measured as oxidative stress biomarkers. E. coli challenge caused oxidative stress in weanling piglets. Dietary supplementation of red osier dogwoods plant products attenuated oxidative stress induced by E. coli challenge in weanling piglets. Further, dietary supplementation of epidermal growth factor also attenuated the generation of free radicals in E. coli challenged weanling piglets. This study concluded that red osier dogwoods as well as EGF can protect weanling piglets from oxidative stress induced by infection en_US
dc.subject Oxidative stress, Piglets, Plant polyphenols, Growth factors en_US
dc.title Regulation of oxidative stress in weaned piglets challenged with Escherichia coli en_US
dc.degree.discipline Animal Science en_US
dc.contributor.examiningcommittee O, Karmin (Animal Science) Nyachoti, Martin (Animal Science) Aluko, Rotimi (Food and Human Nutritional Science) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note October 2017 en_US


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