Polyurethane (PU)-derived photoactive and copper-free clickable surface based on perfluorophenyl azide (PFPA) chemistry
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Date
2013-01
Authors
Liu, Song
Li, Lingdong
Li, Jiang
Kulkarni, Abhilash
Journal Title
Journal ISSN
Volume Title
Publisher
Royal Society of Chemistry
Abstract
The anchoring and capturing roles of perfluorophenyl azide (PFPA) were combined to produce a universal polyurethane (PU)-derived photoactive surface platform (PU-1-PFPA). The resultant platform was confirmed by contact angle, attenuated total reflectance Fourier transform infrared (ATR FT-IR) spectroscopy, atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS) analyses. Upon UV light activation, native heparin was coupled directly onto PU-1-PFPA to yield a substrate with antithrombogenic properties. The same level of antithrombogenic activity was achieved when the recovered heparin was photo-coupled onto PU-1-PFPA. In addition, at room temperature and in the
absence of copper catalysts, PU-1-PFPA achieved oriented immobilization of functional moieties bearing an alkynyl functional group.
Description
Keywords
photoactive and copper-free click reaction, perfluorophenyl azide chemistry
Citation
Li, L.; Li, J.; Kulkarni, A.; Liu, S.* Polyurethane (PU)-derived photoactive and copper-free clickable surface based on perfluorophenyl azide (PFPA) chemistry. J. Mater. Chem. B, 2013,1, 571-582