University of Manitoba Scholarship

Permanent URI for this collection

http://hdl.handle.net/1993/2964

Overview

This collection contains open access research publications authored or co-authored by University of Manitoba researchers. Content within this collection includes pre and post-print versions of articles and book chapters, conference proceedings and technical reports. MSpace is where faculty and students can deposit their research output to meet the open access requirements of grant funding agencies and other related mandates. Deposit is subject to copyright compliance, distribution license and other license restrictions that may be imposed on the work.

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Now showing 1 - 5 of 2195

Open Access
A First-Century Receipt from the Receivers of Public Clothing in Tebtunis (P.Tebt. UC 1607c)
(2019) Gibbs, Matt; Sampson, C. Michael
An edition of a first-century Tebtunis papyrus containing a letter from the receivers of public clothing, with analyses of both this liturgical office as well as the practice of compulsory sale for the supply of military clothing.
Open Access
Together we can build a better future for Manitobans whose lives are impacted by brain injury.
(2024-08-21) Engel, Lisa; Daun, Meredith; Bramadat, Janine; Cohen, Lisa; Plett-Hoffman, Kevin; Louis, Michelle; Thomas, Karen; Walters, Kerri; Karpa, Jane; Russell, Kelly; Brown, Jaime; Plett, Patricia; Chigbo, Ugonna
Acquired brain injury (ABI) is one of the largest diagnostic groups and leading causes of disability around the world, including in Manitoba. Brain injury can affect any area of a person’s functioning, including cognitive/thinking, emotional/mental health, physical, immunological, and behavioral functioning. Due to the widespread effects, ABI can also then change any area of life including family life, housing, employment, leisure transportation, and community participation, with changes often lasting a long time and for many are lifelong changes. These long-term challenges are strongly associated with many detrimental consequences, especially when needs are not met. This includes high rates of homelessness and secondary health concerns. Thus, changes after ABI can create challenging situations for not only the person but also for their families, close others, and communities. Of concern to all citizens, these unmet needs after ABI are costly and have negative effects not just on those directly impacted by ABI, but to all society. In Manitoba people living with ABI, their families, and their close others have many unmet needs directly related to ABI. Brain injury supports and services are chronically underfunded to meet the immediate and long-term needs of ABI-survivors (those living with brain injury), and since the COIVD-19 pandemic ABI supports and services have declines. Of great concern, there lacks a strategy in Manitoba of how to meet the needs of people affected by ABI. While in Canada a bill is progressing through the federal government (i.e., Bill C-277: A national strategy on brain injury), we do not have information on what an effective strategy for brain injury in Manitoba should be. Therefore, we developed the Brain Injury in Manitoba (BIMb) project, and to do this project we formed a diverse and multi-disciplinary project team of people with lived, work, and research-related ABI experience. The goal of the BIMb project is to develop a unified understanding, focus, and recommendations for innovative action, research, advocacy, and policy change that will improve the supports, services, and the quality of life of Manitobans living with ABI. We have addressed our project goal in the Winnipeg region, which was Phase 1 of the BIMb project and is the focus of this report.
Embargo
Will investors’ excitement last? Determinants of investors’ responses to cross-border acquisitions by Chinese firms
(Elsevier, 2023-05-18) Zeng, Rong
Previous studies have found that in the short term, investors in emerging economies tend to react optimistically to cross-border acquisitions. However, studies in both financial economics and strategic management have acknowledged that there may be short-term abnormal returns in the stock market. As such, based on a behavioral perspective on investor valuation, we examine whether and when investors’ initial reactions are sustained using a sample of cross-border acquisitions by Chinese firms from 1998 to 2018. We find that the investor’s initial positive reactions are more likely to be sustained in the long term when (1) a cash payment is used for the acquisition, (2) the acquiring firm has more international acquisition experience, (3) the target firm’s country has a large economy, and (4) the target firm’s country has a culture of high uncertainty avoidance. Our findings extend the behavioral perspective on market reactions to cross-border acquisitions, and we contend that investors’ market valuations are a complex process that relies on various contextual cues. We contribute to an improved understanding of how investors evaluate a firm’s cross-border acquisitions over time.
Open Access
Severe distributive shock, neutrophilic dermatosis, and ST-elevation myocardial infarction in the setting of azathioprine hypersensitivity syndrome
(2024-07-20) Su, Samuel; Wang, Yu M.; Zaborniak, Karver; Hamza, Sate; Jassal, Davinder S.; Blouw, Marcus
Abstract Background Azathioprine is a purine synthesis inhibitor used as an immunosuppressive therapy for many immune-mediated diseases. Azathioprine hypersensitivity reaction is a rare, life-threatening adverse reaction characterized by a range of multisystem manifestations including fever, abdominal pain, arthralgias, erythematous cutaneous eruption, acute renal failure, neutrophilia, and more rarely, distributive shock. Although acute heart failure has been rarely described in association with azathioprine hypersensitivity syndrome, myocardial infarction has, to our knowledge, never been associated with this entity. Case Presentation We describe a case of a 59-year-old male with Crohn’s disease who developed severe azathioprine hypersensitivity syndrome that included distributive shock, neutrophilic dermatosis, and acute coronary syndrome with ST-elevation. Clinical improvement was seen after cessation of azathioprine and administration of glucocorticoid therapy. Conclusion Prompt recognition of azathioprine hypersensitivity syndrome, which can manifest as shock and neutrophilic dermatosis, is key to ensure rapid azathioprine cessation.
Open Access
Interaction between orange juice and < 1 kDa leaf peptides: effect on the antioxidant and antidiabetic related enzyme inhibitory activities
(2024-07-04) Famuwagun, Akinsola A.; Gbadamosi, Saka O.; Taiwo, Kehinde A.; Oyedele, Durodoluwa J.; Adebooye, Odunayo C.; Aluko, Rotimi E.
Abstract Designing a good vehicle for functional ingredients is the major focus of this study. Small molecular weight peptides (< 1 kDa) extracted from amaranth leaf protein (ALP), eggplant leaf protein (ELP) and fluted pumpkin leaf protein (FLP) were incorporated into freshly prepared orange juice at an effective and inhibitory concentrations of the peptides. The rate of degradation of ascorbic acid was more in the control juice (140.06 to 18.43 mg/mL) when compared with juice containing peptides at both storage conditions (140.08 to 32.32 mg/mL). However, the rate of ascorbic acid reduction during storage (refrigerated and ambient) was least in the juice containing peptide, isolated from ELP when compared with the juice samples that contained peptides isolated from ALP and FLP. After the eighth week of storage, juice that contained FLP peptide had greater amounts of residual total phenolic content (370.53 & 432.33 µg GAE/100 mL), juice that contained ALP peptide retained better ability to scavenge DPPH radicals (52.32 & 66.84%) while juice sample that contained ELP retained more metal chelating activities (44.82 and 51.03%). The results of antidiabetic property showed that juice containing peptide isolated from ALP contained greater amounts of α-amylase inhibitory activity (41.50 and 46.89%) while greater amounts of α-glucosidase inhibitory activities were retained in juice that contained peptide isolated from FLP. The results concluded that orange juice may be considered a veritable vehicle for functional ingredients for improved health. Graphical Abstract

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