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Engineering rechargeable antibacterial coatings on steel for efficient inactivation of pathogenic bacteria in the presence of organic matter

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dc.contributor.supervisor Liu, Song (Biosystems Engineering) en_US
dc.contributor.author Mohammadreza, Kazemian
dc.date.accessioned 2018-09-12T16:43:25Z
dc.date.available 2018-09-12T16:43:25Z
dc.date.issued 2018-08-20 en_US
dc.date.submitted 2018-08-20T23:38:09Z en
dc.date.submitted 2018-09-12T14:58:16Z en
dc.identifier.uri http://hdl.handle.net/1993/33321
dc.description.abstract Since 600,000,000 people are affected by foodborne illnesses each year all around the world, food safety has become an important issue. Stainless steel is widely used in the food industry so, it is pivotal to endow stainless steel with potent rechargeable antibacterial function. In this study, a “clickable” coating for stainless steel was developed. Quaternized azido-hydantoin (C1), quaternary ammonium compound (C2), azido-hydantoin (C3), and C1 together with azido-poly (ethylene glycol) (PEG) were bonded to the stainless steel to yield four samples SSMC1, SSMC2, SSMC3, SSMC1-PEG. The coating was stable during the chlorination process which was used to convert the immobilized C1 and C3 to their N-chloramine counterparts. Results reveal that chlorinated SSMC1 sample has the highest antibacterial activity against S. aureus and E. coli in both high protein medium and phosphate-buffered saline even after 5 cycles of chlorination-dechlorination. en_US
dc.subject N-chloramine en_US
dc.subject foodborne illnesses en_US
dc.subject Composite biocide en_US
dc.subject food contact surface en_US
dc.subject antibacterial steel en_US
dc.subject Quaternary Ammonium Compound (QAC) en_US
dc.title Engineering rechargeable antibacterial coatings on steel for efficient inactivation of pathogenic bacteria in the presence of organic matter en_US
dc.degree.discipline Biomedical Engineering en_US
dc.contributor.examiningcommittee Ojo, Olanrewaju (Mechanical Engineering) Franca, Rodrigo (Restorative Dentistry) Narvaez, Claudia (Food and Human Nutritional Sciences) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note October 2018 en_US


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