Engineering rechargeable antibacterial coatings on steel for efficient inactivation of pathogenic bacteria in the presence of organic matter

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dc.contributor.authorMohammadreza, Kazemian
dc.contributor.examiningcommitteeOjo, Olanrewaju (Mechanical Engineering) Franca, Rodrigo (Restorative Dentistry) Narvaez, Claudia (Food and Human Nutritional Sciences)en_US
dc.contributor.supervisorLiu, Song (Biosystems Engineering)en_US
dc.date.accessioned2018-09-12T16:43:25Z
dc.date.available2018-09-12T16:43:25Z
dc.date.issued2018-08-20en_US
dc.date.submitted2018-08-20T23:38:09Zen
dc.date.submitted2018-09-12T14:58:16Zen
dc.degree.disciplineBiomedical Engineeringen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractSince 600,000,000 people are affected by foodborne illnesses each year all around the world, food safety has become an important issue. Stainless steel is widely used in the food industry so, it is pivotal to endow stainless steel with potent rechargeable antibacterial function. In this study, a “clickable” coating for stainless steel was developed. Quaternized azido-hydantoin (C1), quaternary ammonium compound (C2), azido-hydantoin (C3), and C1 together with azido-poly (ethylene glycol) (PEG) were bonded to the stainless steel to yield four samples SSMC1, SSMC2, SSMC3, SSMC1-PEG. The coating was stable during the chlorination process which was used to convert the immobilized C1 and C3 to their N-chloramine counterparts. Results reveal that chlorinated SSMC1 sample has the highest antibacterial activity against S. aureus and E. coli in both high protein medium and phosphate-buffered saline even after 5 cycles of chlorination-dechlorination.en_US
dc.description.noteOctober 2018en_US
dc.identifier.urihttp://hdl.handle.net/1993/33321
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectN-chloramineen_US
dc.subjectfoodborne illnessesen_US
dc.subjectComposite biocideen_US
dc.subjectfood contact surfaceen_US
dc.subjectantibacterial steelen_US
dc.subjectQuaternary Ammonium Compound (QAC)en_US
dc.titleEngineering rechargeable antibacterial coatings on steel for efficient inactivation of pathogenic bacteria in the presence of organic matteren_US
dc.typemaster thesisen_US
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