Infant health is an important comprehensive measure of the health in a society. Experiences during infancy can create durable and heritable patterns of social deprivation and illness ultimately producing health disparities in a population. This thesis sought to determine the relationship between maternal circumstances and infant mortality, morbidity and congenital anomaly rates in Winnipeg, Manitoba, Canada. Using logistic regression models the study explored provincial program screening data and administrative data held. The study found higher rates of congenital anomalies within two parent families and male infants. There was a relationship between hospital readmission rates and social and economic factors. Newborn hospital readmissions were associated with social support factors, while post-neonatal hospital readmissions were associated with contextual factors. Understanding the odds of infant mortality, morbidity and congenital anomaly in relation to different maternal socioeconomic factors may contribute to future health planning and the development of interventions that can improve health equity.