Independent component analysis for maternal-fetal electrocardiography

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Date
2015-01-09
Authors
Marcynuk, Kathryn L.
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Abstract
Separating unknown signal mixtures into their constituent parts is a difficult problem in signal processing called blind source separation. One of the benchmark problems in this area is the extraction of the fetal heartbeat from an electrocardiogram in which it is overshadowed by a strong maternal heartbeat. This thesis presents a study of a signal separation technique called independent component analysis (ICA), in order to assess its suitability for the maternal-fetal ECG separation problem. This includes an analysis of ICA on deterministic, stochastic, simulated and recorded ECG signals. The experiments presented in this thesis demonstrate that ICA is effective on linear mixtures of known simulated or recorded ECGs. The performance of ICA was measured using visual comparison, heart rate extraction, and energy, information theoretic, and fractal-based measures. ICA extraction of clinically recorded maternal-fetal ECGs mixtures, in which the source signals were unknown, were successful at recovering the fetal heart rate.
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blind signal separation, independent component analysis (ICA), complexity measures, ECG signal modelling and analysis, digital signal processing
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