Show simple item record

dc.contributor.author Hausner, Georg
dc.contributor.author Hafez, Mohamed
dc.contributor.author Edgell, David R
dc.date.accessioned 2014-04-10T07:39:17Z
dc.date.available 2014-04-10T07:39:17Z
dc.date.issued 2014-03-10
dc.identifier.citation Mobile DNA. 2014 Mar 10;5(1):8
dc.identifier.uri http://hdl.handle.net/1993/23424
dc.description.abstract Abstract Group I introns are intervening sequences that have invaded tRNA, rRNA and protein coding genes in bacteria and their phages. The ability of group I introns to self-splice from their host transcripts, by acting as ribozymes, potentially renders their insertion into genes phenotypically neutral. Some group I introns are mobile genetic elements due to encoded homing endonuclease genes that function in DNA-based mobility pathways to promote spread to intronless alleles. Group I introns have a limited distribution among bacteria and the current assumption is that they are benign selfish elements, although some introns and homing endonucleases are a source of genetic novelty as they have been co-opted by host genomes to provide regulatory functions. Questions regarding the origin and maintenance of group I introns among the bacteria and phages are also addressed.
dc.rights info:eu-repo/semantics/openAccess
dc.title Bacterial group I introns: mobile RNA catalysts
dc.type Journal Article
dc.type info:eu-repo/semantics/article
dc.language.rfc3066 en
dc.description.version Peer Reviewed
dc.rights.holder Georg Hausner et al.; licensee BioMed Central Ltd.
dc.date.updated 2014-04-10T07:39:18Z
dc.identifier.doi http://dx.doi.org/10.1186/1759-8753-5-8


Files in this item

This item appears in the following Collection(s)

  • Research Publications [1174]
    This collection contains full text research publications authored or co-authored by University of Manitoba researchers.

Show simple item record

View Statistics