• Libraries
    • Log in to:
    View Item 
    •   MSpace Home
    • Faculty of Graduate Studies (Electronic Theses and Practica)
    • FGS - Electronic Theses and Practica
    • View Item
    •   MSpace Home
    • Faculty of Graduate Studies (Electronic Theses and Practica)
    • FGS - Electronic Theses and Practica
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Retrograde cardioplegia, effec s of coronary venous perfusion on myocardial energy metabolism, contractile function and myocardial perfusion in neonatal hearts

    Thumbnail
    View/Open
    MQ32206.pdf (5.197Mb)
    Date
    1998-06-01
    Author
    Oriaku, Godwin I.
    Metadata
    Show full item record
    Abstract
    Objective. This study tested the hypothesis that a heart maintained in arrest by retrograde cardioplegia (RC) can recover metabolic and contractile function to a level comparable to that of antegrade cardioplegia (AC). Methods. Isolated Langendorff piglet hearts were subjected a protocol consisting of 30 minutes of control perfusion, 45 minutes of arrest, and 30 minutes of reperfusion. During the control and reperfusion periods, the hearts were pelfused using Krebs-Henseleit (K-H) solution. Cardioplegic arrest was induced with two minutes of AC. Arrest was maintained for 43 minutes with continuous RC in group 1. The hearts in roup 2 were subjected to 45 minutes of continuous AC. Myocardial energy metabolism and contractile function in the two groups were compared by assessing energy metabolites using $\sp{31}$P MR spectroscopy and determining myocardial O$\sb2$ consumption (MVO$\sb2)$ and measuring intraventricular pressure. (Abstract shortened by UMI.)
    URI
    http://hdl.handle.net/1993/1231
    Collections
    • FGS - Electronic Theses and Practica [25525]

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of MSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    Statistics

    View Usage Statistics

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV