Nothing about us without us: a priority-setting partnership for research in type 1 diabetes and exercise

dc.contributor.authorKlaprat, Nika
dc.contributor.examiningcommitteeSibley, Kathryn (Community Health Sciences) Marks, Seth (Pediatrics and Child Health)en_US
dc.contributor.supervisorMcGavock, Jonathan (Kinesiology and Recreation Management) Duhamel, Todd (Kinesiology and Recreation Management)en_US
dc.date.accessioned2019-08-28T20:19:29Z
dc.date.available2019-08-28T20:19:29Z
dc.date.issued2019en_US
dc.date.submitted2019-07-25T18:21:10Zen
dc.date.submitted2019-08-28T20:14:30Zen
dc.degree.disciplineKinesiology and Recreation Managementen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractBackground: Engaging patients in health research can align study questions and research designs with relevant priorities. Priorities for exercise-related research for persons living with type 1 diabetes (T1D) remain unclear. Methods: Individuals with lived experience of T1D were engaged in a modified James Lind Alliance process to identify research priorities in T1D and exercise. An online survey gathered research questions from patients, caregivers and healthcare providers across Canada. Submissions were qualitatively analyzed and the resulting long-list was distributed to a 12-person stakeholder steering committee. Members individually ranked their top ten questions and rankings were collated to create a short-list, discussed in a final workshop. Results: 115 individuals across Canada completed the survey, yielding 194 research questions. After qualitative analysis, 38 questions were long-listed and following committee ranking, 24 questions were short-listed for workshop discussions. The top 10 were: (1) What explains the individual variation in the response to exercise?; (2) Which is the best for maintaining glycemic stability and glucose tolerance: aerobic training, strength training, or a combination of both? If a combination, does the order matter?; (3) What modes of exercise produce the best health benefits while maintaining tight glycemic control?; (4) What dietary plans can safely and effectively be followed for an active lifestyle in type 1 diabetes without compromising pre- and post-exercise glycemic control?; (5) What is the optimal time of day and exercise prescription (example: how often, what type, how intense) in order to maintain ideal glycemic control and insulin sensitivity?; (6) What is the best method of preventing post-exercise hypo- or hyperglycemia?; (7) Will certain glycemic ranges before starting exercise consistently result in hypo- or hyperglycemia?; (8) What effect can various levels of hydration have on blood sugar levels during and after exercise?; (9) How does hypo- or hyperglycemia affect muscle growth and strength training progress, or vice versa?; and (10) What is the effect of climate/temperature on blood sugar control during exercise and what causes this effect?. Conclusion: This list could inform future iterations of exercise studies for persons with T1D. The prioritized questions focused on lifestyle differences, optimal glucose control and performance progression.en_US
dc.description.noteOctober 2019en_US
dc.identifier.urihttp://hdl.handle.net/1993/34103
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectType 1 diabetesen_US
dc.subjectExerciseen_US
dc.subjectPhysical activityen_US
dc.subjectPriority-settingen_US
dc.subjectPatient engagementen_US
dc.titleNothing about us without us: a priority-setting partnership for research in type 1 diabetes and exerciseen_US
dc.typemaster thesisen_US
local.subject.manitobayesen_US
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