Colorectal cancer screening in Manitoba: analysis of factors associated with program participation and outcomes

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dc.contributor.authorFindlay-Shirras, Lisa
dc.contributor.examiningcommitteeHardy, Krista (Surgery) Helewa, Ramzi (Surgery)en_US
dc.contributor.supervisorPark, Jason (Surgery)en_US
dc.date.accessioned2020-04-07T17:47:04Z
dc.date.available2020-04-07T17:47:04Z
dc.date.copyright2020-03-26
dc.date.issued2020-03-26en_US
dc.date.submitted2020-03-26T18:41:07Zen_US
dc.degree.disciplineSurgeryen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractIntroduction Fecal-based (FT) colorectal cancer (CRC) screening is designed to prevent cancer or diagnose it early when it is most amenable to treatment. This study assessed the socio-demographic and clinical factors associated with participation and outcomes of a population-based provincial CRC screening program. Methods This retrospective cohort study included individuals age 50-74 who were eligible to participate in Manitoba’s CRC screening program from 2007-2014. Sociodemographic factor and clinical variable subgroup analyses were performed using multivariable logistic regression. Results 118,096 screening FTs were completed, and 3081 follow-up colonoscopies were completed. On multivariable analysis, screening participation is associated with age, sex, deprivation index, and geography. Age and sex were associated with identifying advanced neoplasia and non-advanced adenomas on colonoscopy. Conclusions Our study suggests CRC screening participation and outcomes are associated with specific sociodemographic and clinical factors. Through identification of disparities and barriers to participation, access, or timely investigations, we can inform and direct future program initiatives.en_US
dc.description.noteMay 2020en_US
dc.identifier.urihttp://hdl.handle.net/1993/34654
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectColonen_US
dc.subjectColorectalen_US
dc.subjectCanceren_US
dc.subjectScreeningen_US
dc.titleColorectal cancer screening in Manitoba: analysis of factors associated with program participation and outcomesen_US
dc.typemaster thesisen_US
local.subject.manitobayesen_US
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