House of Hollow Bones is a psychologically driven novella that explores the psychological impacts of mental illness and traumatic loss within familial relationships. The story follows the lives of two sisters, Edith and Angela, and their father, Frank. It is composed in three sections, each one written from a different character’s perspective. The plot begins when Frank and Angela get into a fight at a family dinner at Edith’s house. Edith must leave the room with her son, Jacob, who has autism, because the noise and arguing will upset him. She spends the moments in her bedroom recalling memories from her past. Edith harbours a secret that only her sister is aware of. Jacob is not biologically Adrien’s child. After a string of failed attempts at pregnancy and miscarriages Edith goes to spend the weekend with Angela. They go to a party and Edith cheats on Adrien and becomes pregnant. Angela swears to keep Edith’s secret, but after Edith moves back from Toronto, Edith is not sure if Angela is still trustworthy. Edith becomes anxious about her sister’s mental state. Angela’s substance abuse has escalated, and she has become obsessed with finding their mother, Tommy, who abandoned their family when the girls were young. Angela blames Frank for Tommy’s leaving and accuses him of hiding information about Tommy’s whereabouts. Before Angela can confront her father again, Frank commits suicide. While Edith and Angela sort through his belongings, Edith finds a stack of letters from Tommy but hides them from Angela. After finding nothing that helps her with her search for Tommy at Frank’s apartment, Angela turns to alcohol. Later that night, she ends up falling in her shower and becoming concussed. Edith comes to watch over her during her recovery and decides to share Tommy’s letters with Angela. Although Tommy is now given a voice through these letters, Angela and Edith cannot agree on a narrative. Although this is the case, they find a way to re-discover and recover their relationship.