Microencapsulation for effective delivery of essential oils to improve gut health in pigs
| dc.contributor.author | Omonijo, Faith | |
| dc.contributor.examiningcommittee | Nyachoti, Martin (Animal Science) Gong, Joshua (Animal Science) Liu, Song (Biosystmens Engineering) | en_US |
| dc.contributor.supervisor | Yang, Chengbo (Animal Science) | en_US |
| dc.date.accessioned | 2019-01-07T16:45:07Z | |
| dc.date.available | 2019-01-07T16:45:07Z | |
| dc.date.issued | 2018-11-26 | en_US |
| dc.date.submitted | 2018-12-11T00:02:38Z | en |
| dc.degree.discipline | Animal Science | en_US |
| dc.degree.level | Master of Science (M.Sc.) | en_US |
| dc.description.abstract | Alternatives to in-feed antibiotics (e.g. thymol) is important to maintain sustainable pig production. In this study, the anti-inflammatory effect of thymol was considered and a novel microparticles was developed to deliver thymol and lauric acid to pig gut. The results suggest that thymol can enhance barrier function, reduce ROS production and pro-inflammatory cytokines in IPEC-J2 cells during inflammation. The release of thymol and lauric acid from developed microparticles was determined in vitro. Microparticles with 2% alginate solution displayed a slow release of thymol and lauric acid in the SSF (21.2 ± 2.3%; 36 ± 1.1%), SGF (73.7 ± 6.9%; 54.8 ± 1.7%) and SIF (99.1 ± 1.2%; 99.1 ± 0.6%), respectively, whereas, the microparticles without alginate showed a rapid release of thymol and lauric acid from the SSF (79.9 ± 11.8%; 84.9 ± 9.4%), SGF (92.5 ± 3.5%; 75.8 ± 5.9%) and SIF (93.3 ± 9.4%; 93.3 ± 4.6%), respectively. | en_US |
| dc.description.note | February 2019 | en_US |
| dc.identifier.citation | Essential oils as alternatives to antibiotic in swine production (APA) | en_US |
| dc.identifier.citation | Development of novel microparticles for effective delivery of thymol and lauric acid to pig intestinal tract (ACS) | en_US |
| dc.identifier.uri | http://hdl.handle.net/1993/33624 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | Encapsulation, Thymol, Barrier functions, IPEC-J2 cells, Lauric acid, Microparticles, Slow release | en_US |
| dc.title | Microencapsulation for effective delivery of essential oils to improve gut health in pigs | en_US |
| dc.type | master thesis | en_US |