Mesorectal excision: a surgical and pathological audit in Winnipeg
| dc.contributor.author | Liu, Wenjun | |
| dc.contributor.examiningcommittee | Wightman, Robert (Pathology) Hochman, David (Surgery) | en_US |
| dc.contributor.supervisor | Shih, Francis (Pathology) | en_US |
| dc.date.accessioned | 2018-01-12T20:35:30Z | |
| dc.date.available | 2018-01-12T20:35:30Z | |
| dc.date.issued | 2017 | |
| dc.degree.discipline | Pathology | en_US |
| dc.degree.level | Master of Science (M.Sc.) | en_US |
| dc.description.abstract | Colorectal cancer is the malignant neoplasm of the colon or rectum. Total Mesorectal Excision refers to the complete sharp surgical resection of the perirectal soft tissue, resulting in a smooth, circumferential radial margin. The completeness of a mesorectal excision can be evaluated based on the integrity of the radial margin, which is crucial for pathological examination, as it is important in predicting local and systemic recurrence. Our objectives of this study are to assess the quality factors of the mesorectal excisions and to discuss the importance of the proper macroscopic and microscopic pathological examinations of rectal and rectosigmoid cancer in Winnipeg. This retrospective cohort study of mesorectal excision specimens with rectal carcinomas in Winnipeg from 2012 – 2015 includes 453 cases. Statistical analyses show the local incomplete mesorectal excision percentage is 10.9 %. Surgical quality is highly related to tumour location, radial margin involvement, the surgeon’s training background, and volume. | en_US |
| dc.description.note | February 2018 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1993/32829 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | Rectal cancer | en_US |
| dc.subject | Mesorectal excision quality | en_US |
| dc.subject | Surgery | en_US |
| dc.subject | Pathology report | en_US |
| dc.subject | Audit | en_US |
| dc.subject | Quirke method | en_US |
| dc.title | Mesorectal excision: a surgical and pathological audit in Winnipeg | en_US |
| dc.type | master thesis | en_US |
| local.subject.manitoba | yes | en_US |