Bacterial isolate and resistance patterns of deep neck infections: The Manitoba experience
| dc.contributor.author | Scherle, Kurt | |
| dc.contributor.examiningcommittee | Stoykewych, Andrew (Dental Diagnostics and Surgical Sciences) Curran, John (Dental Diagnostics and Surgical Sciences) McNicol, Archie (Oral Biology) | en_US |
| dc.contributor.supervisor | Darichuk, Lee (Dental Diagnostics and Surgical Sciences) | en_US |
| dc.date.accessioned | 2014-09-03T20:24:23Z | |
| dc.date.available | 2014-09-03T20:24:23Z | |
| dc.date.issued | 2014-09-03 | |
| dc.degree.discipline | Dental Diagnostic and Surgical Sciences | en_US |
| dc.degree.level | Master of Dentistry (M.Dent.) | en_US |
| dc.description.abstract | Objective: The purpose of the study is to identify bacteria isolate patterns in deep neck infections managed by Oral & Maxillofacial Surgeons at a tertiary care centre in Manitoba, and analyze resistance profiles of the bacteria to specific antibiotics. Patients and Methods: A 2-year retrospective chart review on a population treated at a tertiary academic centre with deep neck infections surgically managed by the Oral & Maxillofacial Surgery service. 53 patients underwent surgical incision and drainage, received intravenous antibiotics, and had microbiological testing completed. Results: There were 25 male (47%) and 28 female (53%) patients treated by incision and drainage in an operating room setting and who had microbiological swabs obtained at the time of surgery. The submandibular space was most commonly involved (64%), followed by buccal space (34%) and lateral pharyngeal space (17%). Twenty five patients had involvement of multiple spaces. The total number of spaces involved was 90. Of the 53 patients treated, 46 grew bacterial cultures. The most commonly isolated bacteria were Streptococcus viridans, Anaerobic non-spore-forming gram positive bacilli, and Prevotella oralis. On microbiological analysis, anaerobic gram-negative rods grew in 38 cases (72%) and aerobic gram-positive cocci in 33 cases (62%). Resistance to penicillin G was highest (70%). Conclusions: Patients undergoing surgical incision and drainage by the Oral & Maxillofacial Surgery service tended towards multiple space involvement with submandibular, buccal, and lateral pharyngeal being most common. Cultures more often revealed growth of anaerobes than aerobes. Gram-negative rods and gram-positive cocci were most prevalent. Resistance was highest to the penicillin family of antibiotics, followed by clindamycin. | en_US |
| dc.description.note | October 2014 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1993/23957 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | Deep | en_US |
| dc.subject | Neck | en_US |
| dc.subject | Infection | en_US |
| dc.subject | Antibiotic | en_US |
| dc.subject | Resistance | en_US |
| dc.subject | Odontogenic | en_US |
| dc.subject | Maxillofacial | en_US |
| dc.subject | Oral | en_US |
| dc.title | Bacterial isolate and resistance patterns of deep neck infections: The Manitoba experience | en_US |
| dc.type | master thesis | en_US |
| local.subject.manitoba | yes | en_US |