Construction of optimal designs in polynomial regression models
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Date
2012-10-03
Authors
Zhu, Chao
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Abstract
We consider a class of optimization problems in which the aim is to find some
optimizing probability distributions. One particular example is optimal design.
We first review the optimal design theory, and determine the optimality
conditions using directional derivatives. We then construct optimal designs
for various polynomial regression models by finding the analytic solutions and
by using a class of algorithms. We consider a practical problem, namely a
radiation-dosage example, and discuss important aspects of optimal design
throughout this example.
We also construct optimal designs for various polynomial regression models
with more than one design variable. We consider another practical problem,
namely a vocabulary-growth study. We then construct D-optimal and
c-optimal designs for various models with and without the interaction term
and the second order terms in design variables. We also develop strategies for
constructing designs by using the properties of the directional derivatives.
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Keywords
optimal, designs