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The effects of Manitoban wild rice on cardiovascular risk factors in low density lipoprotein receptor knock-out (LDLr-KO) mice

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dc.contributor.supervisor Moghadasian, Mohammed (Human Nutritional Sciences) Beta, Trust (Food Science) en_US
dc.contributor.author Goh, Chun Yan
dc.date.accessioned 2012-04-05T19:11:29Z
dc.date.available 2012-04-05T19:11:29Z
dc.date.issued 2012-04-05
dc.identifier.uri http://hdl.handle.net/1993/5262
dc.description.abstract Wild rice is recognized as a whole grain by U.S. FDA and it is rich in polyphenol compounds. This study aimed to investigate the potential cardiovascular benefits of wild rice in LDLr-KO mice. Seventy-two male and female mice were randomly assigned to 3 different diet groups, control diet (a), white diet (b), and wild diet (c) for 24 weeks. Dietary cholesterol 0.06 % (w/w) was added in all diets, and digestible carbohydrate source was replaced with: (a) commercial carbohydrate source (sucrose and corn starch); (b) white rice; (c) wild rice. Incorporation of wild rice in the diet distinctly increases total phenolic content of the diet. Plasma total cholesterol, VLDL, and LDL cholesterol levels declined significantly in wild diet group. The hypocholesterolemic properties of wild rice were mainly attributed to the increased excretion of fecal cholesterol. Our data suggest that substituting refined grains with wild rice may potentially lower cardiovascular risks. en_US
dc.rights info:eu-repo/semantics/openAccess
dc.subject Wild rice en_US
dc.subject Cardiovascular disease en_US
dc.title The effects of Manitoban wild rice on cardiovascular risk factors in low density lipoprotein receptor knock-out (LDLr-KO) mice en_US
dc.type info:eu-repo/semantics/masterThesis
dc.type master thesis en_US
dc.degree.discipline Human Nutritional Sciences en_US
dc.contributor.examiningcommittee Aliani, Michel (Human Nutritional Sciences) Netticadan, Thomas (Physiology) en_US
dc.degree.level Master of Science (M.Sc.) en_US
dc.description.note May 2012 en_US


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