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dc.contributor.author Marshall, Jean S
dc.contributor.author Warrington, Richard
dc.contributor.author Watson, Wade
dc.contributor.author Kim, Harold L
dc.date.accessioned 2018-10-01T03:23:05Z
dc.date.issued 2018-09-12
dc.identifier.citation Allergy, Asthma & Clinical Immunology. 2018 Sep 12;14(Suppl 2):49
dc.identifier.uri https://doi.org/10.1186/s13223-018-0278-1
dc.identifier.uri http://hdl.handle.net/1993/33491
dc.description.abstract Abstract Beyond structural and chemical barriers to pathogens, the immune system has two fundamental lines of defense: innate immunity and adaptive immunity. Innate immunity is the first immunological mechanism for fighting against an intruding pathogen. It is a rapid immune response, initiated within minutes or hours after aggression, that has no immunologic memory. Adaptive immunity, on the other hand, is antigen-dependent and antigen-specific; it has the capacity for memory, which enables the host to mount a more rapid and efficient immune response upon subsequent exposure to the antigen. There is a great deal of synergy between the adaptive immune system and its innate counterpart, and defects in either system can provoke illness or disease, such as inappropriate inflammation, autoimmune diseases, immunodeficiency disorders and hypersensitivity reactions. This article provides a practical overview of innate and adaptive immunity, and describes how these host defense mechanisms are involved in both heath and illness.
dc.rights info:eu-repo/semantics/openAccess
dc.title An introduction to immunology and immunopathology
dc.type Journal Article
dc.type info:eu-repo/semantics/article
dc.language.rfc3066 en
dc.rights.holder The Author(s)
dc.date.updated 2018-10-01T03:23:05Z


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