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dc.contributor.authorStrutinsky, Jeanna Brandy Leeen_US
dc.date.accessioned2007-06-01T19:21:38Z
dc.date.available2007-06-01T19:21:38Z
dc.date.issued2000-09-01T00:00:00Zen_US
dc.identifier.urihttp://hdl.handle.net/1993/2339
dc.description.abstractIn bacteria, stationary phase is a time of intricate cellular metabolic and physiological changes necessary for the maintenance of essential cell functions and resistance to environmental stresses, such as oxidative stress. This study investigated 'perR'; a locus potentially involved in the hydrogen peroxide resistance of 'Escherichia coli' in stationary phase. The strain UM397 containing a mutation in 'perR' was created as part of this study and showed 13.6 fold greater sensitivity to H2O2 in stationary phase when compared to its parent strain MG1655. This suggested that PerR is involved in oxidative stress resistance in stationary phase. Further, the predicted sequence of PerR is similar to LysR-type transcriptional regulators, suggesting a regulatory role for the protein.en_US
dc.format.extent5140582 bytes
dc.format.extent184 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoengen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleIdentification and genetic mapping of perR, a novel stationary phase gene that mediates oxidative stress protection in Escherichia colien_US
dc.typeinfo:eu-repo/semantics/masterThesis
dc.typemaster thesisen_US
dc.degree.disciplineMicrobiologyen_US
dc.degree.levelMaster of Science (M.Sc.)en_US


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