Urinary Iodine Clearance following Iodinated Contrast Administration: A Comparison of Euthyroid and Postthyroidectomy Subjects

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dc.contributor.authorHo, Janice D.
dc.contributor.authorTsang, James F.
dc.contributor.authorScoggan, Kylie A.
dc.contributor.authorLeslie, William D.
dc.date.accessioned2015-05-14T16:08:58Z
dc.date.available2015-05-14T16:08:58Z
dc.date.issued2014-11-12
dc.date.updated2015-03-29T13:26:37Z
dc.description.abstractPurpose. To compare iodine clearance following iodinated contrast administration in thyroidectomised thyroid cancer patients and euthyroid individuals. Methods. A convenience population (6 thyroidectomised thyroid cancer patients and 7 euthyroid controls) was drawn from patients referred for iodinated contrast-enhanced computed tomography (CT) studies. Subjects had sequential urine samples collected up to 6 months (50 samples from the thyroidectomised and 63 samples from the euthyroid groups). -tests and generalised estimating equations (GEE) were used to test for group differences in urinary iodine creatinine ratios. Results. Groups had similar urinary iodine creatinine ratios at baseline, with a large increase 2 weeks following iodinated contrast (). Both groups had a return of urinary iodine creatinine ratios to baseline by 4 weeks, with no significant group differences overall or at any time point. Conclusions. Thyroidectomised patients did not have a significantly different urinary iodine clearance than euthyroid individuals following administration of iodinated contrast. Both had a return of urinary iodine creatinine ratios to baseline within 4 weeks.
dc.description.versionPeer Reviewed
dc.identifier.citationJanice D. Ho, James F. Tsang, Kylie A. Scoggan, and William D. Leslie, “Urinary Iodine Clearance following Iodinated Contrast Administration: A Comparison of Euthyroid and Postthyroidectomy Subjects,” Journal of Thyroid Research, vol. 2014, Article ID 580569, 4 pages, 2014. doi:10.1155/2014/580569
dc.identifier.urihttp://dx.doi.org/10.1155/2014/580569
dc.identifier.urihttp://hdl.handle.net/1993/30473
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2014 Janice D. Ho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleUrinary Iodine Clearance following Iodinated Contrast Administration: A Comparison of Euthyroid and Postthyroidectomy Subjects
dc.typeJournal Article
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