Systematic review of interventions for depression and anxiety in persons with inflammatory bowel disease

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dc.contributor.authorFiest, Kirsten M
dc.contributor.authorBernstein, Charles N
dc.contributor.authorWalker, John R
dc.contributor.authorGraff, Lesley A
dc.contributor.authorHitchon, Carol A
dc.contributor.authorPeschken, Christine A
dc.contributor.authorZarychanski, Ryan
dc.contributor.authorAbou-Setta, Ahmed
dc.contributor.authorPatten, Scott B
dc.contributor.authorSareen, Jitender
dc.contributor.authorBolton, James
dc.contributor.authorSinger, Alexander
dc.contributor.authorMarrie, Ruth A
dc.date.accessioned2016-08-12T14:02:55Z
dc.date.available2016-08-12T14:02:55Z
dc.date.issued2016-08-12
dc.date.updated2016-08-12T06:03:05Z
dc.description.abstractAbstract Background Depression and anxiety are common in inflammatory bowel disease (IBD) and can affect disease outcomes, including quality of life and success of disease treatment. Successful management of psychiatric comorbidities may improve outcomes, though the effectiveness of existing treatments in IBD is unknown. Methods We searched multiple online databases from inception until March 25, 2015, without restrictions on language, date, or location of publication. We included controlled clinical trials conducted in persons with IBD and depression or anxiety. Two independent reviewers reviewed all abstracts and full-text articles and extracted information including trial and participant characteristics. We also assessed the risk of bias. Results Of 768 unique abstracts, we included one trial of pharmacological anxiety treatment in IBD (48 participants), which found an improvement in anxiety symptoms (p < 0.001). There was a high risk of bias in this trial. We found no controlled clinical trials on the treatment of depression in persons with IBD and depression and no controlled clinical trials reporting on psychological interventions for anxiety or depression in IBD. Conclusions Only one trial examined an intervention for anxiety in adults with IBD and no trials studied depression in adults with IBD. The level of evidence is low because of the risk of bias and limited evidence.
dc.identifier.citationBMC Research Notes. 2016 Aug 12;9(1):404
dc.identifier.urihttp://dx.doi.org/10.1186/s13104-016-2204-2
dc.identifier.urihttp://hdl.handle.net/1993/31577
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderThe Author(s)
dc.titleSystematic review of interventions for depression and anxiety in persons with inflammatory bowel disease
dc.typeJournal Article
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