Towards a next-generation preclinical PET/MR insert with improved timing and count rate performance

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dc.contributor.authorVan Elburg, Devin
dc.contributor.examiningcommitteeMammei, Juliette (Physics and Astronomy) Major, Arkady (Electrical and Computer Engineering) Ingleby, Harry (Physics and Astronomy)en_US
dc.contributor.supervisorGoertzen, Andrew (Physics and Astronomy)en_US
dc.date.accessioned2018-08-22T21:12:42Z
dc.date.available2018-08-22T21:12:42Z
dc.date.issued2018-08en_US
dc.date.submitted2018-08-10T16:01:22Zen
dc.degree.disciplinePhysics and Astronomyen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractOur group has previously developed a PET insert for simultaneous PET/MRI imaging. The insert consists of silicon photomultipliers (SiPMs) with a resistor-based charge division multiplexing readout circuit. Some limitations include a 2.5ns coincidence time resolution (CTR), a relatively long signal duration of >1.5us, and a 1.3us paralyzable dead time. This thesis focuses on characterizing these limitations and demonstrating a second-generation detector module for improved timing and count rate performance. First, optical coupling optimization using acrylic polymer tapes versus conventional silicone optical grease was investigated. Second, CTR and signal duration was reduced by using an enhanced readout board equipped with three new SiPM-type detectors. Last, dead time of the system was reduced by minimizing the sampling number of the OpenPET acquisition system. Future work includes design modification to accommodate the first-generation scintillator footprint and potentially to adapt the OpenPET acquisition system to read in SiPM `fast' outputs.en_US
dc.description.noteOctober 2018en_US
dc.identifier.urihttp://hdl.handle.net/1993/33221
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectPositron emission tomographyen_US
dc.subjectPreclinical PET/MR insertsen_US
dc.subjectCoincidence time resolutionen_US
dc.subjectSilicon photomultipliersen_US
dc.subjectMulti-pixel photon countersen_US
dc.subjectDead timeen_US
dc.titleTowards a next-generation preclinical PET/MR insert with improved timing and count rate performanceen_US
dc.typemaster thesisen_US
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