Coronary Spasm in Neurosurgical Patients and Role of Trigeminocardiac Reflex

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dc.contributor.authorChowdhury, Tumul
dc.contributor.authorMeuwly, Cyrill
dc.contributor.authorSandu, Nora
dc.contributor.authorCappellani, Ronald B.
dc.contributor.authorSchaller, Bernhard
dc.date.accessioned2014-08-14T06:45:45Z
dc.date.available2014-08-14T06:45:45Z
dc.date.issued2014-1-27
dc.date.updated2014-08-14T06:45:46Z
dc.description.abstractBackground. Coronary artery spasm (CAS) is a rarely reported complication in neurosurgical patients and its main causative mechanism was attributed to vagal mediated responses. However, these may be the unusual manifestations of trigeminal cardiac reflex (TCR) which is a well established brain stem reflex observed in various neurosurgical patients. Methods and Results. In this review, we have searched for the case reports/papers related to intraoperative coronary spasm in neurosurgical patients and described the role of TCR in this regard. TCR is a possible mechanism in producing CAS in most of the cases in which stimulation occurred at or near the vicinity of trigeminal nerve. It is likely that TCR mediated coronary spasm may be a physiological mechanism and not related to actual myocardial insult apparent by cardiac enzymes or echocardiography studies in most of the cases. Some common risk factors may also exist related to occurrence of CAS as well as TCR. Conclusions. In conclusion, neurosurgical procedures occurring at the vicinity of trigeminal nerve may produce CAS even in previously healthy patients and may produce catastrophic consequences. There is a need for future reports and experimental studies on the interaction of TCR and pathophysiological mechanisms related to CAS.
dc.description.versionPeer Reviewed
dc.identifier.citationTumul Chowdhury, Cyrill Meuwly, Nora Sandu, Ronald B. Cappellani, and Bernhard Schaller, “Coronary Spasm in Neurosurgical Patients and Role of Trigeminocardiac Reflex,” Neurology Research International, vol. 2014, Article ID 974930, 5 pages, 2014. doi:10.1155/2014/974930
dc.identifier.doihttp://dx.doi.org/10.1155/2014/974930
dc.identifier.urihttp://hdl.handle.net/1993/23766
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2014 Tumul Chowdhury et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleCoronary Spasm in Neurosurgical Patients and Role of Trigeminocardiac Reflex
dc.typeJournal Article
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