Bridging the gap: a Canadian perspective on translational kidney research

Simple item page
dc.contributor.authorMolnar, Amber O
dc.contributor.authorYuen, Darren A
dc.contributor.authorTangri, Navdeep
dc.contributor.authorJensen, Victor L
dc.date.accessioned2014-08-28T19:02:54Z
dc.date.available2014-08-28T19:02:54Z
dc.date.issued2014-08-29
dc.date.updated2014-08-28T19:02:55Z
dc.description.abstractAbstract Purpose of review Chronic kidney disease affects approximately 3 million Canadians. Ongoing investment in high quality kidney research is needed to improve the care of patients with kidney disease. The barriers to translating such research are discussed in this review. Sources of information Personal knowledge, research funding body websites, and published reports. Findings In this review, we discuss the meaning of the term translational research and present some of the programs aimed at ensuring efficient translation of scientific discoveries with a discussion of the barriers to translation. We highlight some successes and barriers to kidney research translation using recent examples of research in Canadian nephrology. We present the following examples of kidney research: (1) research aimed at identifying the causative genes for inherited kidney diseases; (2) recent discoveries in cell-based therapies for kidney disease; (3) an examination of the impact of acute kidney injury in renal transplant patients; and (4) the development of a kidney failure risk equation to improve prognosis accuracy. Limitations This review focuses on research conducted by the authors. Implications The process of research translation is prolonged and challenging and therefore requires resources, patience, and careful planning. With increased awareness and understanding of the barriers to research translation, researchers and funding bodies can work together to increase the rate at which important research findings reach clinical practice and improve the care of patients with kidney disease.
dc.description.versionPeer Reviewed
dc.identifier.citationCanadian Journal of Kidney Health and Disease. 2014 Aug 29;1(1):18
dc.identifier.doihttp://dx.doi.org/10.1186/s40697-014-0018-5
dc.identifier.urihttp://hdl.handle.net/1993/23914
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderAmber O Molnar et al.; licensee BioMed Central Ltd.
dc.titleBridging the gap: a Canadian perspective on translational kidney research
dc.typeJournal Article
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
s40697-014-0018-5.xml
Size:
169.21 KB
Format:
Extensible Markup Language
Description:
Download
Thumbnail Image
Name:
s40697-014-0018-5.pdf
Size:
330.05 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.17 KB
Format:
Item-specific license agreed to upon submission
Description:
Download
Collections
University of Manitoba Scholarship
Rady Faculty of Health Sciences Scholarly Works