A Survey of Current Practices and Factors Associated with Health Care Professionals' Use of Probiotics
| dc.contributor.author | Londono Calle, Yenly Catherine | |
| dc.contributor.examiningcommittee | Chiu, Aaron (Community Health Sciences) Friel, James (Human Nutritional Sciences) Sherman, Philip (University of Toronto) | en_US |
| dc.contributor.supervisor | Diehl-Jones, William (Nursing) Heaman, Maureen (Nursing) | en_US |
| dc.date.accessioned | 2016-09-23T19:40:04Z | |
| dc.date.available | 2016-09-23T19:40:04Z | |
| dc.date.issued | 2016 | |
| dc.degree.discipline | Applied Health Sciences | en_US |
| dc.degree.level | Doctor of Philosophy (Ph.D.) | en_US |
| dc.description.abstract | Probiotics are live microorganisms which confer a health benefit to the host. The literature strongly supports the benefits of probiotic therapy in preterm infant populations, specifically in the prevention of necrotizing enterocolitis (NEC) and mortality. To this end, probiotics are routinely given to premature infants in several European and Asian countries. However, in spite of the current evidence and neonatal feeding practices elsewhere, probiotic supplements are rarely prescribed in nurseries in North America. Furthermore, there is little or no literature on factors which affect clinical decision-making regarding probiotic supplementation. The study implemented a cross-sectional descriptive survey. The purpose of this study was to: (i) describe current practices involving probiotic supplementation of preterm infant enteral feeds; and (ii) identify factors that affect willingness of health care professionals to support the use of probiotics. Probiotic use was examined in Neonatal Intensive Care Units (NICUs) in Canada and the United States using two cross-sectional internet-based surveys. Survey #1 focused on current practices and targeted neonatologists who serve as clinical directors or department heads. The results were analysed using descriptive statistics. Survey #2 addressed factors that affect probiotic supplementation of preterm infant feedings, and had two versions: the first version targeted physicians and nurse practitioners whereas version 2 targeted neonatal nurses. The development of Survey #2 was guided by the Theoretical Domain Framework which evaluates factors which may affect the willingness of Health Care Professionals to support the use of probiotics in neonatal practice. The results of survey #2 were analysed using Chi-Square, Fisher’s Exact Test, and One-Way ANOVA. The results of the study indicated that only a small proportion of NICUs are administering probiotics to preterm infants and practices vary. The most significant factors influencing clinical decision-making regarding probiotic supplementation were knowledge about probiotics and the evidence, perceptions about the evidence and safety of probiotics, and knowledge about probiotics and clinical guidelines. Improving knowledge about probiotics, addressing safety issues of probiotics products, expanding the evidence base, and developing clinical guidelines may contribute to increased use of probiotics in NICUs. | en_US |
| dc.description.note | October 2016 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1993/31854 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | Probiotics, Premature Infants, decision, Survey, Health Care Professionals, Medical Directors, Neonatal Intensive Care Unit, nutrition, Nurses, Neonatologist, Neonatal Nurse | en_US |
| dc.title | A Survey of Current Practices and Factors Associated with Health Care Professionals' Use of Probiotics | en_US |
| dc.type | doctoral thesis | en_US |