Normative Data for Bone Mass in Healthy Term Infants from Birth to 1 Year of Age

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dc.contributor.authorGallo, Sina
dc.contributor.authorVanstone, Catherine A.
dc.contributor.authorWeiler, Hope A.
dc.date.accessioned2015-05-14T16:31:06Z
dc.date.available2015-05-14T16:31:06Z
dc.date.issued2012-10-2
dc.date.updated2015-03-29T13:32:08Z
dc.description.abstractFor over 2 decades, dual-energy X-ray absorptiometry (DXA) has been the gold standard for estimating bone mineral density (BMD) and facture risk in adults. More recently DXA has been used to evaluate BMD in pediatrics. However, BMD is usually assessed against reference data for which none currently exists in infancy. A prospective study was conducted to assess bone mass of term infants (37 to 42 weeks of gestation), weight appropriate for gestational age, and born to healthy mothers. The group consisted of 33 boys and 26 girls recruited from the Winnipeg Health Sciences Center (Manitoba, Canada). Whole body (WB) as well as regional sites of the lumbar spine (LS 1–4) and femur was measured using DXA (QDR 4500A, Hologic Inc.) providing bone mineral content (BMC) for all sites and BMD for spine. During the year, WB BMC increased by 200% ( versus  g), spine BMC by 130% ( versus  g), and femur BMC by 190% ( versus  g). Spine BMD increased by 14% ( versus  g/cm2) during the year. This data, representing the accretion of bone mass during the first year of life, is based on a representative sample of infants and will aid in the interpretation of diagnostic DXA scans by researchers and health professionals.
dc.description.versionPeer Reviewed
dc.identifier.citationSina Gallo, Catherine A. Vanstone, and Hope A. Weiler, “Normative Data for Bone Mass in Healthy Term Infants from Birth to 1 Year of Age,” Journal of Osteoporosis, vol. 2012, Article ID 672403, 8 pages, 2012. doi:10.1155/2012/672403
dc.identifier.urihttp://dx.doi.org/10.1155/2012/672403
dc.identifier.urihttp://hdl.handle.net/1993/30497
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2012 Sina Gallo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleNormative Data for Bone Mass in Healthy Term Infants from Birth to 1 Year of Age
dc.typeJournal Article
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