Design, development, and evaluation of a clinical system for breast microwave imaging

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dc.contributor.authorSolis Nepote, Mario Alejandro
dc.contributor.examiningcommitteeMoussavi, Zahra (Electrical and Computer Engineering) Unger, Bertram (Mechanical Engineering) Torchia, Mark (Surgery)en_US
dc.contributor.supervisorPistorius, Stephen (Physics and Astronomy)en_US
dc.date.accessioned2018-01-11T20:04:28Z
dc.date.available2018-01-11T20:04:28Z
dc.date.issued2017
dc.degree.disciplineBiomedical Engineeringen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractBreast Microwave Imaging (BMI) has a promising future for breast cancer detection. In radar-based approaches, backscattered signals are reconstructed into images of reflections from the breast tissues to visualize tumors, which are sources of larger scatter than normal tissue. This thesis presents the development and evaluation of a new radar-based, BMI system designed for clinical use. Breast phantoms were developed with synthetic skin, morphologically accurate 3D-printed materials, and dielectrically appropriate tissue surrogates. Phantom scans with the system resulted in artifact-free images, accurate detection of a 1.5-cm-wide tumor, and signal-to-clutter ratios greater than 20 dB. The comfort and safety of the system were validated during a pre-clinical trial involving 11 asymptomatic volunteers. The effects of antenna positioning errors in BMI systems were characterized using the developed system and a hemispherical breast phantom. This work established a set of minimal and ideal tolerances for antenna positioning equipment in BMI systems.en_US
dc.description.noteFebruary 2018en_US
dc.identifier.urihttp://hdl.handle.net/1993/32800
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectBreast Microwave Imagingen_US
dc.subjectBMIen_US
dc.subjectMedical Imagingen_US
dc.subjectRadar systemen_US
dc.subjectBreast cancer detectionen_US
dc.subjectMedical deviceen_US
dc.subjectBiomedical designen_US
dc.subjectDesign of medical devicesen_US
dc.subjectMechanical designen_US
dc.subjectBreast phantomsen_US
dc.subjectPositioning performanceen_US
dc.subjectProduct developmenten_US
dc.titleDesign, development, and evaluation of a clinical system for breast microwave imagingen_US
dc.typemaster thesisen_US
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