Modulating brain networks associated with cognitive deficits in Parkinson’s disease

dc.contributor.authorBeheshti, Iman
dc.contributor.authorKo, Ji H
dc.date.accessioned2021-04-01T05:02:00Z
dc.date.issued2021-03-10
dc.date.updated2021-04-01T05:02:00Z
dc.description.abstractAbstract Parkinson’s disease (PD) is a relatively well characterised neurological disorder that primarily affects motor and cognitive functions. This paper reviews on how transcranial direct current stimulation (tDCS) can be used to modulate brain networks associated with cognitive deficits in PD. We first provide an overview of brain network abnormalities in PD, by introducing the brain network modulation approaches such as pharmacological interventions and brain stimulation techniques. We then present the potential underlying mechanisms of tDCS technique, and specifically highlight how tDCS can be applied to modulate brain network abnormality associated with cognitive dysfunction among PD patients. More importantly, we address the limitations of existing studies and suggest possible future directions, with the aim of helping researchers to further develop the use of tDCS technique in clinical settings.
dc.identifier.citationMolecular Medicine. 2021 Mar 10;27(1):24
dc.identifier.urihttps://doi.org/10.1186/s10020-021-00284-5
dc.identifier.urihttp://hdl.handle.net/1993/35390
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderThe Author(s)
dc.titleModulating brain networks associated with cognitive deficits in Parkinson’s disease
dc.typeJournal Article
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