Effect of nanosilver particles on metabolism and cortisol release in rainbow trout (Oncorhynchus mykiss)

dc.contributor.authorMurray, Laura
dc.contributor.examiningcommitteeBlanchfield, Paul (Biological Sciences) Roth, Jim (Biological Sciences) Enders, Eva (Fisheries and Oceans Canada)en_US
dc.contributor.supervisorRennie, Michael (Biological Sciences)en_US
dc.date.accessioned2016-01-14T20:14:12Z
dc.date.available2016-01-14T20:14:12Z
dc.date.issued2015
dc.degree.disciplineBiological Sciencesen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractNanosilver (nAg) is a nanoparticle incorporated into products for its antimicrobial properties that causes diverse toxic effects. This study investigated the effects of nAg on metabolic rate and stress response in rainbow trout (Oncorhynchus mykiss Walbaum 1792). Fish were exposed to environmentally-relevant concentrations of nAg (average 0.28 μg l-1) and higher (average 47.60 μg l-1) for 28 days (d). Measurements of cortisol, growth, condition (K), and hepatosomatic index (HSI) were analyzed, as well as metabolic measurements. Cortisol concentrations were higher in all nAg exposures, and were significantly elevated in high exposures. No significant effects of nAg exposure were observed on metabolic variables, growth or condition. There was a significant effect of time and treatment on HSI, but no discernible trend. There was also a significant increase in cortisol in fish measured for metabolic variables. Overall nAg was seen to engage the stress response, but not affect metabolism or morphometric measures.en_US
dc.description.noteFebruary 2016en_US
dc.identifier.urihttp://hdl.handle.net/1993/31083
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectRespirometryen_US
dc.subjectFishen_US
dc.subjectContaminanten_US
dc.subjectEndocrineen_US
dc.subjectPhysiologyen_US
dc.titleEffect of nanosilver particles on metabolism and cortisol release in rainbow trout (Oncorhynchus mykiss)en_US
dc.typemaster thesisen_US
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