2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema

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dc.contributor.authorBowen, Tom
dc.contributor.authorCicardi, Marco
dc.contributor.authorFarkas, Henriette
dc.contributor.authorBork, Konrad
dc.contributor.authorLonghurst, Hilary J
dc.contributor.authorZuraw, Bruce
dc.contributor.authorAygoeren-Pursun, Emel
dc.contributor.authorCraig, Timothy
dc.contributor.authorBinkley, Karen
dc.contributor.authorHebert, Jacques
dc.contributor.authorRitchie, Bruce
dc.contributor.authorBouillet, Laurence
dc.contributor.authorBetschel, Stephen
dc.contributor.authorCogar, Della
dc.contributor.authorDean, John
dc.contributor.authorDevaraj, Ramachand
dc.contributor.authorHamed, Azza
dc.contributor.authorKamra, Palinder
dc.contributor.authorKeith, Paul K
dc.contributor.authorLacuesta, Gina
dc.contributor.authorLeith, Eric
dc.contributor.authorLyons, Harriet
dc.contributor.authorMace, Sean
dc.contributor.authorMako, Barbara
dc.contributor.authorNeurath, Doris
dc.contributor.authorPoon, Man-Chiu
dc.contributor.authorRivard, Georges-Etienne
dc.contributor.authorSchellenberg, Robert
dc.contributor.authorRowan, Dereth
dc.contributor.authorRowe, Anne
dc.contributor.authorStark, Donald
dc.contributor.authorSur, Smeeksha
dc.contributor.authorTsai, Ellie
dc.contributor.authorWarrington, Richard
dc.contributor.authorWaserman, Susan
dc.contributor.authorAmeratunga, Rohan
dc.contributor.authorBernstein, Jonathan
dc.contributor.authorBjorkander, Janne
dc.contributor.authorBrosz, Kristylea
dc.contributor.authorBrosz, John
dc.contributor.authorBygum, Anette
dc.contributor.authorCaballero, Teresa
dc.contributor.authorFrank, Mike
dc.contributor.authorFust, George
dc.contributor.authorHarmat, George
dc.contributor.authorKanani, Amin
dc.contributor.authorKreuz, Wolfhart
dc.contributor.authorLevi, Marcel
dc.contributor.authorLi, Henry
dc.contributor.authorMartinez-Saguer, Inmaculada
dc.contributor.authorMoldovan, Dumitru
dc.contributor.authorNagy, Istvan
dc.contributor.authorNielsen, Erik W
dc.contributor.authorNordenfelt, Patrik
dc.contributor.authorReshef, Avner
dc.contributor.authorRusicke, Eva
dc.contributor.authorSmith-Foltz, Sarah
dc.contributor.authorSpath, Peter
dc.contributor.authorVarga, Lilian
dc.contributor.authorXiang, Zhi Y
dc.date.accessioned2012-09-07T15:07:16Z
dc.date.available2012-09-07T15:07:16Z
dc.date.issued2010-07-28
dc.date.updated2012-09-07T15:07:17Z
dc.description.abstractAbstract Background We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art review: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Objective To update the International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema (circa 2010). Methods The Canadian Hereditary Angioedema Network (CHAEN)/Réseau Canadien d'angioédème héréditaire (RCAH) http://www.haecanada.com and cosponsors University of Calgary and the Canadian Society of Allergy and Clinical Immunology (with an unrestricted educational grant from CSL Behring) held our third Conference May 15th to 16th, 2010 in Toronto Canada to update our consensus approach. The Consensus document was reviewed at the meeting and then circulated for review. Results This manuscript is the 2010 International Consensus Algorithm for the Diagnosis, Therapy and Management of Hereditary Angioedema that resulted from that conference. Conclusions Consensus approach is only an interim guide to a complex disorder such as HAE and should be replaced as soon as possible with large phase III and IV clinical trials, meta analyses, and using data base registry validation of approaches including quality of life and cost benefit analyses, followed by large head-to-head clinical trials and then evidence-based guidelines and standards for HAE disease management.
dc.description.versionPeer Reviewed
dc.identifier.citationAllergy, Asthma & Clinical Immunology. 2010 Jul 28;6(1):24
dc.identifier.doihttp://dx.doi.org/10.1186/1710-1492-6-24
dc.identifier.urihttp://hdl.handle.net/1993/8618
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderTom Bowen et al.; licensee BioMed Central Ltd.
dc.title2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema
dc.typeJournal Article
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