Development and validation of a low noise signal acquisition protocol for inner ear evoked potentials

dc.contributor.authorKumaragamage, Chathura Lahiru
dc.contributor.examiningcommitteeBlakley, Brian (Otolaryngology) Kordi, Behzad (Elec. & Comp. Eng.)en_US
dc.contributor.supervisorMoussavi, Zahra (Elec. & Comp. Eng.) Lithgow, Brian (Elec. & Comp. Eng.)en_US
dc.date.accessioned2013-08-22T14:38:06Z
dc.date.available2013-08-22T14:38:06Z
dc.date.issued2013-07en_US
dc.degree.disciplineBiomedical Engineeringen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractA low noise signal acquisition protocol is required for inner ear evoked response recordings. In this work, a parallel amplifier approach was investigated to implement a bio-signal amplifier with low voltage noise (<5nV/√Hz), and low current noise (~2fA/√Hz). A modified ear electrode was investigated to reduce biological interference and thermal noise due to high impedance electrodes. A physical model to simulate electrical activity of the inner ear was developed to evaluate the accuracy of detecting vestibular field potentials (FPs) in the presence of various noise sources. Muscle activity and noise generated from the recording apparatus were found to be the dominating sources, degrading performance of FP extraction. Contributions from this work include: the design, implementation, and validation of a bio-signal amplifier with <5nV/√Hz voltage noise, and a low impedance electrode development and placement protocol. As a result, a signal-to-noise-ratio improvement of ~11dB (compared to the current protocol) was achieved.en_US
dc.description.noteOctober 2013en_US
dc.identifier.citationKumaragamage C, Edwards R, Moussavi Z, Lithgow B., "Implementation of a Gelatin Model to Both Simulate and Facilitate Detection of Inner Ear Biological Activity", 35th Annual International IEEE EMBS Conference", pp. 4545-4548, 2013.en_US
dc.identifier.urihttp://hdl.handle.net/1993/22063
dc.language.isoengen_US
dc.publisherIEEE EMBSen_US
dc.rightsopen accessen_US
dc.subjectbiological signal amplifieren_US
dc.subjectElectrovestibulographyen_US
dc.subjectparallel amplifieren_US
dc.subjectultra low noiseen_US
dc.titleDevelopment and validation of a low noise signal acquisition protocol for inner ear evoked potentialsen_US
dc.typemaster thesisen_US
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