Is iron deficiency in the absence of anemia associated with fatigue in inflammatory bowel disease?

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dc.contributor.authorGoldenberg, Benjamin
dc.contributor.authorGraff, Lesley A.
dc.contributor.authorClara, Ian
dc.contributor.authorZarychanski, Ryan
dc.contributor.authorWalker, John R.
dc.contributor.authorCarr, Rachel
dc.contributor.authorRogala, Linda
dc.contributor.authorMiller, Norine
dc.contributor.authorBernstein, Charles N.
dc.date.accessioned2015-05-11T20:14:49Z
dc.date.available2015-05-11T20:14:49Z
dc.date.issued2013-09
dc.description.abstractOBJECTIVES: We explored whether iron deficiency in the absence of anemia is associated with fatigue in inflammatory bowel disease (IBD). METHODS: We assessed iron deficiency and anemia in 280 participants from the population-based Manitoba IBD Cohort Study. RESULTS: Iron deficiency was identified in 20% with Crohn's disease and 27% with ulcerative colitis. Anemia was identified overall in 50 (18%), with 230 who were nonanemic. In the nonanemic subgroup, there were no significant differences between iron-deficient and -sufficient groups in mean fatigue levels or proportions with problematic fatigue. There was no unique contribution of iron deficiency to problematic fatigue after adjustment for active disease and anemia. CONCLUSIONS: There was no evidence of an association between iron deficiency and fatigue in the absence of anemia, suggesting that iron deficiency is not a clinically relevant contributor to fatigue in IBD.en_US
dc.identifier.citationAm J Gastroenterol. 2013 Sep;108(9):1392-7en_US
dc.identifier.urihttp://dx.doi.org/10.1038/ajg.2013.14
dc.identifier.urihttp://hdl.handle.net/1993/30433
dc.language.isoengen_US
dc.publisherAmerican Journal Gastroenterologyen_US
dc.relation.ispartofseries108(9);1392-7
dc.rightsopen accessen_US
dc.subjectIron Deficiencyen_US
dc.subjectanemiaen_US
dc.subjectInflammatory Bowel Diseaseen_US
dc.subjectIBDen_US
dc.subjectBernsteinen_US
dc.titleIs iron deficiency in the absence of anemia associated with fatigue in inflammatory bowel disease?en_US
dc.typeArticleen_US
dc.typeDataseten_US
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