Optimal designs for maximum likelihood estimation and factorial structure design

dc.contributor.authorChowdhury, Monsur
dc.contributor.examiningcommitteeMandal, Saumen (Statistics) Muthukumarana, Saman (Statistics) Yang, Po (Statistics) Appadoo, Srimantoorao (Supply Chain Management) Bhaumik, Dulal (University of Illinois)en_US
dc.contributor.supervisorMandal, Saumen (Statistics)en_US
dc.date.accessioned2016-09-06T20:01:54Z
dc.date.available2016-09-06T20:01:54Z
dc.date.issued2016
dc.degree.disciplineStatisticsen_US
dc.degree.levelDoctor of Philosophy (Ph.D.)en_US
dc.description.abstractThis thesis develops methodologies for the construction of various types of optimal designs with applications in maximum likelihood estimation and factorial structure design. The methodologies are applied to some real data sets throughout the thesis. We start with a broad review of optimal design theory including various types of optimal designs along with some fundamental concepts. We then consider a class of optimization problems and determine the optimality conditions. An important tool is the directional derivative of a criterion function. We study extensively the properties of the directional derivatives. In order to determine the optimal designs, we consider a class of multiplicative algorithms indexed by a function, which satisfies certain conditions. The most important and popular design criterion in applications is D-optimality. We construct such designs for various regression models and develop some useful strategies for better convergence of the algorithms. The remaining thesis is devoted to some important applications of optimal design theory. We first consider the problem of determining maximum likelihood estimates of the cell probabilities under the hypothesis of marginal homogeneity in a square contingency table. We formulate the Lagrangian function and remove the Lagrange parameters by substitution. We then transform the problem to one of maximizing some functions of the cell probabilities simultaneously. We apply this problem to some real data sets, namely, a US Migration data, and a data on grading of unaided distance vision. We solve another estimation problem to determine the maximum likelihood estimation of the parameters of the latent variable models such as Bradley-Terry model where the data come from a paired comparisons experiment. We approach this problem by considering the observed frequency having a binomial distribution and then replacing the binomial parameters in terms of optimal design weights. We apply this problem to a data set from American League Baseball Teams. Finally, we construct some optimal structure designs for comparing test treatments with a control. We introduce different structure designs and establish their properties using the incidence and characteristic matrices. We also develop methods of obtaining optimal R-type structure designs and show how such designs are trace, A- and MV-optimal.en_US
dc.description.noteOctober 2016en_US
dc.identifier.urihttp://hdl.handle.net/1993/31637
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectOptimal design, directional derivative, maximum likelihood estimation, structure designen_US
dc.titleOptimal designs for maximum likelihood estimation and factorial structure designen_US
dc.typedoctoral thesisen_US
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