Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia

dc.contributor.authorWuerz, Terry C
dc.contributor.authorBow, Eric J
dc.contributor.authorSeftel, Matthew D
dc.date.accessioned2016-06-07T18:02:28Z
dc.date.available2016-06-07T18:02:28Z
dc.date.issued2013-1-1
dc.date.updated2016-06-07T06:53:53Z
dc.description.abstractIn 2012, Canadian pharmacies experienced a shortage of trimethoprim-sulfamethoxazole tablets. Drug shortages may result in unintended clinical consequences such as infection with pathogens against which the alternative medication is ineffective. This is highlighted in the present article, which describes a case of brain abscess due to Nocardia species that developed while receiving dapsone as an alternative for prophylaxis against Pneumocystis jirovecii pneumonia in a highly immune-suppressed patient. Clinicians should be cognizant of these issues when prescribing alternative agents.
dc.description.versionPeer Reviewed
dc.identifier.citationTerry C Wuerz, Eric J Bow, and Matthew D Seftel, “Potential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia,” Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 24, no. 3, pp. 159-161, 2013. doi:10.1155/2013/805797
dc.identifier.urihttp://dx.doi.org/10.1155/2013/805797
dc.identifier.urihttp://hdl.handle.net/1993/31345
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2013 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titlePotential Consequences of Essential Drug Shortages in Canada: Brain Abscess due to Nocardia farcinica Associated with Dapsone Prophylaxis for Pneumocystis jirovecii Pneumonia
dc.typeJournal Article
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