Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats
| dc.contributor.author | Green, Kathy H. | en_US |
| dc.date.accessioned | 2007-05-22T15:12:08Z | |
| dc.date.available | 2007-05-22T15:12:08Z | |
| dc.date.issued | 2001-03-01T00:00:00Z | en_US |
| dc.degree.discipline | Foods and Nutrition | en_US |
| dc.degree.level | Master of Science (M.Sc.) | en_US |
| dc.description.abstract | An investigation was conducted in 8 to 18 year old children to determine interrelationships among Type 1 diabetes (DM 1), bone mass, nutrient intake and physical activity. Bone mineral content (BMC, g), bone area (BA, cm 2), and bone mineral density (BMD, g/cm2) were measured by dual-energy x-ray absorptiometry in children with (n = 27 females, 24 males) and without (n = 34 females, 34 males) DM 1. Nutrient intake was assessed using 3-day food records and physical activity by a validated questionnaire. Data was analyzed by two-way ANOVA and correlation analysis. Based on the results a second investigation was undertaken to study further the role of insulin in bone development, and the effect of n-3 PUFA on bone development in insulin deficiency. Weanling male Sprague-Dawley rats (n = 80) were randomly assigned to one of six groups: saline injection + pair-weigh (n = 20) or ad lib feeding (n = 20), or streptozotocin injection to induce insulin deficiency + ad lib feeding (n = 40). Animals were fed diet containing either soy oil or fish oil (menhaden + corn oil). (Abstract shortened by UMI.) | en_US |
| dc.format.extent | 10278413 bytes | |
| dc.format.extent | 184 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.format.mimetype | text/plain | |
| dc.identifier.uri | http://hdl.handle.net/1993/1989 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.title | Type 1 diabetes and bone mass, interrelationships with nutrient intake and physical activity in children and with dietary fish oil in weanling rats | en_US |
| dc.type | master thesis | en_US |