Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment

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dc.contributor.authorCook, Victoria J
dc.contributor.authorManfreda, Jure
dc.contributor.authorHershfield, Earl S
dc.date.accessioned2016-06-08T17:54:58Z
dc.date.available2016-06-08T17:54:58Z
dc.date.issued2004-1-1
dc.date.updated2016-06-07T06:59:44Z
dc.description.abstractBACKGROUND: Tuberculous lymphadenitis (TBL) is an important form of extrapulmonary tuberculosis (TB). Recent studies have shown an increase in TBL in Canada.OBJECTIVES: To determine the incidence of TBL in Manitoba and to identify the characteristics associated with its presentation, diagnosis and treatment.METHODS: Population data from the Manitoba Health Population Registry, the First Nations and Inuit Health Branch of Health Canada, and Statistics Canada were used to calculate incidence. Case characteristics and outcomes were determined by a systematic, retrospective review of all cases between January 1, 1990 and December 31, 2000.RESULTS: One-hundred forty seven cases of TBL were identified during the study period; 77% confirmed by culture; 68% women. TBL was found in Canadian-born/nonstatus Aboriginal (12%), status Aboriginal (29%) and foreign-born (59%) populations. Incidence of TBL was 1.17 per 100,000 person years (95% CI 0.98 to 1.36). The highest incidence was in status Aboriginals over 65 years (16.85 per 100,000 person years; 95% CI 3.37 to 30.33). TBL is seen most often in Western Pacific women. The most common presentation was a single, enlarged cervical node (80%). No atypical mycobacterium was found. Drug resistance occurred in 13% of cases and only in the foreign-born. Cure rates (81%) were influenced by comorbidity and burden of TB disease. Relapse occurred in 8.1 per 1000 person years of follow-up (95% CI 1.7 to 23.7).CONCLUSIONS: Respiratory physicians, who manage the majority of TB disease in Canada, need to remain aware that TB is an important and treatable cause of enlarged lymph nodes.
dc.description.versionPeer Reviewed
dc.identifier.citationVictoria J Cook, Jure Manfreda, and Earl S Hershfield, “Tuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment,” Canadian Respiratory Journal, vol. 11, no. 4, pp. 279-286, 2004. doi:10.1155/2004/826501
dc.identifier.urihttp://dx.doi.org/10.1155/2004/826501
dc.identifier.urihttp://hdl.handle.net/1993/31417
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleTuberculous Lymphadenitis in Manitoba: Incidence, Clinical Characteristics and Treatment
dc.typeJournal Article
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