The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol

Simple item page
dc.contributor.authorLester, Richard T
dc.contributor.authorMills, Edward J
dc.contributor.authorKariri, Antony
dc.contributor.authorRitvo, Paul
dc.contributor.authorChung, Michael
dc.contributor.authorJack, William
dc.contributor.authorHabyarimana, James
dc.contributor.authorKaranja, Sarah
dc.contributor.authorBarasa, Samson
dc.contributor.authorNguti, Rosemary
dc.contributor.authorEstambale, Benson
dc.contributor.authorNgugi, Elizabeth
dc.contributor.authorBall, T Blake
dc.contributor.authorThabane, Lehana
dc.contributor.authorKimani, Joshua
dc.contributor.authorGelmon, Lawrence
dc.contributor.authorAckers, Marta
dc.contributor.authorPlummer, Francis A
dc.date.accessioned2012-12-20T16:17:18Z
dc.date.available2012-12-20T16:17:18Z
dc.date.issued2009-09-22
dc.date.updated2012-12-20T16:17:18Z
dc.description.abstractAbstract Background The objectives are to compare the effectiveness of cell phone-supported SMS messaging to standard care on adherence, quality of life, retention, and mortality in a population receiving antiretroviral therapy (ART) in Nairobi, Kenya. Methods and Design A multi-site randomized controlled open-label trial. A central randomization centre provided opaque envelopes to allocate treatments. Patients initiating ART at three comprehensive care clinics in Kenya will be randomized to receive either a structured weekly SMS ('short message system' or text message) slogan (the intervention) or current standard of care support mechanisms alone (the control). Our hypothesis is that using a structured mobile phone protocol to keep in touch with patients will improve adherence to ART and other patient outcomes. Participants are evaluated at baseline, and then at six and twelve months after initiating ART. The care providers keep a weekly study log of all phone based communications with study participants. Primary outcomes are self-reported adherence to ART and suppression of HIV viral load at twelve months scheduled follow-up. Secondary outcomes are improvements in health, quality of life, social and economic factors, and retention on ART. Primary analysis is by 'intention-to-treat'. Sensitivity analysis will be used to assess per-protocol effects. Analysis of covariates will be undertaken to determine factors that contribute or deter from expected and determined outcomes. Discussion This study protocol tests whether a novel structured mobile phone intervention can positively contribute to ART management in a resource-limited setting. Trial Registration Trial Registration Number: NCT00830622
dc.description.versionPeer Reviewed
dc.identifier.citationTrials. 2009 Sep 22;10(1):87
dc.identifier.doihttp://dx.doi.org/10.1186/1745-6215-10-87
dc.identifier.urihttp://hdl.handle.net/1993/14163
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderRichard T Lester et al.; licensee BioMed Central Ltd.
dc.titleThe HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol
dc.typeJournal Article
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
1745-6215-10-87.pdf
Size:
522.49 KB
Format:
Adobe Portable Document Format
Description:
Download
Thumbnail Image
Name:
1745-6215-10-87.xml
Size:
89.41 KB
Format:
Extensible Markup Language
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed to upon submission
Description:
Download
Collections
University of Manitoba Scholarship
Rady Faculty of Health Sciences Scholarly Works