Effects of lutein and docosahexaenoic acid enriched egg consumption on visual function in older adults: Implications for age-related macular degeneration

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dc.contributor.authorWalchuk, Chelsey
dc.contributor.examiningcommitteeAliani, Michel (Human Nutritional Sciences) Bellan, Lorne (Ophthalmology & Human Nutritional Sciences) Netticadan, Thomas (Physiology & Pathophysiology)en_US
dc.contributor.supervisorSuh, Miyoung (Human Nutritional Sciences) House, James (Human Nutritional Sciences)en_US
dc.date.accessioned2017-04-12T14:46:31Z
dc.date.available2017-04-12T14:46:31Z
dc.date.issued2017
dc.degree.disciplineHuman Nutritional Sciencesen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractThis study investigated whether lutein and DHA enriched egg consumption can improve electrophysiological retina function for the prevention of age-related macular degeneration in Caucasian older adults. Thirty (male: n=11, female: n=19) healthy Caucasian older adults (64.0 ± 3.4 years) consumed two lutein and DHA enriched eggs (0.87 mg lutein/day, 220 mg DHA/day) daily for six weeks. Retina function, plasma and red blood cell (RBC) DHA, plasma lutein, lipid profiles, and lipoprotein subfractions were assessed at day 0 and 6 wks. The maximum amplitude of scotopic a-wave and photopic b-wave significantly increased along with plasma DHA concentrations No significant alterations in plasma Chol, HDL-Chol, LDL-Chol, triacylglycerides, plasma lutein and RBC DHA were present. A significant increase in large HDL particles and a decrease in intermediate sized HDL particles occurred. This study suggests that consuming two lutein and DHA enriched eggs daily may improve electrophysiological retina function without adversely altering plasma lipids in Caucasian older adults.en_US
dc.description.noteMay 2017en_US
dc.identifier.urihttp://hdl.handle.net/1993/32212
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectEnriched eggsen_US
dc.subjectOlder adultsen_US
dc.subjectLuteinen_US
dc.subjectDocosahexaenoic aciden_US
dc.subjectElectroretinogramen_US
dc.subjectRetina functionen_US
dc.titleEffects of lutein and docosahexaenoic acid enriched egg consumption on visual function in older adults: Implications for age-related macular degenerationen_US
dc.typemaster thesisen_US
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