Enterococcal Bacteremia in a Tertiary Care Centre in Winnipeg

dc.contributor.authorMadani, Tariq AA
dc.contributor.authorKabani, Amin
dc.contributor.authorOrr, Pamela
dc.contributor.authorNicolle, Lindsay
dc.date.accessioned2016-06-09T15:17:29Z
dc.date.available2016-06-09T15:17:29Z
dc.date.issued1999-1-1
dc.date.updated2016-06-07T07:02:23Z
dc.description.abstractOBJECTIVE: To review experience with enterococcal bacteremia before the emergence of vancomycin-resistant enterococcus at a tertiary care teaching hospital.DESIGN: Retrospective chart review of episodes of enterococcal bacteremia identified through the clinical microbiology laboratory from January 1990 to December 1994. Antimicrobial susceptibilities were performed for all isolates and pulsed-field gel electrophoresis for genetic typing of selected strains.RESULTS: One hundred and twenty-six episodes of bacteremia were identified in 109 patients: 108 Enterococcus faecalis, 13 Enterococcus faecium, four both E faecalis and E faecium, and one Enterococcus durans. Enterococcal isolates occurred with polymicrobial bacteremia in 62 (49%) episodes. The most common sites of infection were central venous catheters (45%) and the urinary tract (21%). Enterococcal bacteremia was usually nosocomially acquired (88%), and associated with older age, instrumentation, and prior or current antimicrobial therapy. Overall mortality was 22%, and 7.2% was partially or fully attributable to enterococcal bacteremia. Resistance to ampicillin, high level gentamicin and high level streptomycin were 0%, 32% and 31% for E faecalis, respectively, and 44%, 0% and 47% for E faecium, respectively.CONCLUSIONS: During this review, the frequency and impact of enterococcal bacteremia at this institution was relatively limited. Isolates resistant to ampicillin and aminoglycosides were emerging, but differences in patient outcomes were similar for resistant and susceptible isolates.
dc.description.versionPeer Reviewed
dc.identifier.citationTariq AA Madani, Amin Kabani, Pamela Orr, and Lindsay Nicolle, “Enterococcal Bacteremia in a Tertiary Care Centre in Winnipeg,” Canadian Journal of Infectious Diseases, vol. 10, no. 1, pp. 57-63, 1999. doi:10.1155/1999/454985
dc.identifier.urihttp://dx.doi.org/10.1155/1999/454985
dc.identifier.urihttp://hdl.handle.net/1993/31455
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 1999 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleEnterococcal Bacteremia in a Tertiary Care Centre in Winnipeg
dc.typeJournal Article
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