Eosinophilic myocarditis: two case reports and review of the literature

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dc.contributor.authorRizkallah, Jacques
dc.contributor.authorDesautels, Angela
dc.contributor.authorMalik, Amrit
dc.contributor.authorZieroth, Shelley
dc.contributor.authorJassal, Davinder
dc.contributor.authorHussain, Farrukh
dc.contributor.authorCordova, Francisco
dc.date.accessioned2013-12-23T20:05:04Z
dc.date.available2013-12-23T20:05:04Z
dc.date.issued2013-12-17
dc.date.updated2013-12-23T20:05:04Z
dc.description.abstractAbstract Background Eosinophilic myocarditis is a rare and often under-diagnosed subtype of myocarditis with only around 30 cases published in the medical literature. In this article we present two patients with eosinophilic myocarditis with the aim to demonstrate the often elusive nature of the disease and present the current scientific literature on this topic. Case presentation A 76 years old Caucasian gentleman and a 36 years old Aboriginal gentleman both presenting with heart failure symptoms were eventually diagnosed with eosinophilic myocarditis after extensive evaluation. Their presentation, assessment, and medical management is explored in this article. Conclusions Eosinophilic myocarditis remains a rare and likely under-diagnosed subtype of myocarditis. The key features of this disease include myocardial injury in the setting of non-contributory coronary artery disease. Endomyocardial biopsy remains the definitive gold standard for diagnosis of noninfectious eosinophilic myocarditis. Non-invasive cardiac imaging in the setting of peripheral eosinophilia can be strongly suggestive of eosinophilic myocarditis with potential for earlier diagnosis. Failure to diagnose eosinophilic myocarditis and the delay of therapy may lead to irreversible myocardial injury. Therapies for this disease have yet to be validated in large prospective studies.
dc.description.versionPeer Reviewed
dc.identifier.citationBMC Research Notes. 2013 Dec 17;6(1):538
dc.identifier.doihttp://dx.doi.org/10.1186/1756-0500-6-538
dc.identifier.urihttp://hdl.handle.net/1993/22729
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderJacques Rizkallah et al.; licensee BioMed Central Ltd.
dc.titleEosinophilic myocarditis: two case reports and review of the literature
dc.typeJournal Article
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