Embryonic stages in cerebellar afferent development

dc.contributor.authorRahimi-Balaei, Maryam
dc.contributor.authorAfsharinezhad, Pegah
dc.contributor.authorBailey, Karen
dc.contributor.authorBuchok, Matthew
dc.contributor.authorYeganeh, Behzad
dc.contributor.authorMarzban, Hassan
dc.date.accessioned2015-10-08T21:12:37Z
dc.date.available2015-10-08T21:12:37Z
dc.date.issued2015-06-11
dc.date.updated2015-10-06T22:54:27Z
dc.description.abstractAbstract The cerebellum is important for motor control, cognition, and language processing. Afferent and efferent fibers are major components of cerebellar circuitry and impairment of these circuits causes severe cerebellar malfunction, such as ataxia. The cerebellum receives information from two major afferent types – climbing fibers and mossy fibers. In addition, a third set of afferents project to the cerebellum as neuromodulatory fibers. The spatiotemporal pattern of early cerebellar afferents that enter the developing embryonic cerebellum is not fully understood. In this review, we will discuss the cerebellar architecture and connectivity specifically related to afferents during development in different species. We will also consider the order of afferent fiber arrival into the developing cerebellum to establish neural connectivity.
dc.identifier.citationCerebellum & Ataxias. 2015 Jun 11;2(1):7
dc.identifier.urihttp://dx.doi.org/10.1186/s40673-015-0026-y
dc.identifier.urihttp://hdl.handle.net/1993/30897
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderBalaei et al.
dc.titleEmbryonic stages in cerebellar afferent development
dc.typeJournal Article
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