The effect of lubricant composition on the wear behaviour of polyethylene for orthopaedic applications

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dc.contributor.authorWong, Leah
dc.contributor.examiningcommitteeWu, Christine (Mechanical Engineering) Thomson, Douglas (Computer and Electrical Engineering)en_US
dc.contributor.supervisorBrandt, Jan-Mels (Mechanical Engineering) Wyss, Urs (Mechanical Engineering)en_US
dc.date.accessioned2013-08-22T13:06:27Z
dc.date.available2013-08-22T13:06:27Z
dc.date.issued2013-08-22
dc.degree.disciplineMechanical and Manufacturing Engineeringen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractThe composition of orthopaedic wear testing lubricants used to mimic synovial fluid (SF) is known to significantly affect in vitro polyethylene (PE) wear; however, some wear testing standards may be promoting the use of lubricants that are not clinically relevant. The present thesis evaluated the biochemical composition of human osteoarthritic and periprosthetic SF in order to propose changes to lubricant specifications in current wear testing standards. Using this data, pin-on-disc wear tests were conducted to explore the effects of more clinically relevant lubricants on PE wear. Results showed that wear decreased using a more clinically relevant lubricant. Samples of these lubricants were biochemically evaluated and compared to the SF results previously obtained, which showed that current standards for wear testing lubricants are biochemically different from SF. The findings from the present thesis encourage the modification of standardized lubricant specifications to improve wear testing protocols and guarantee clinically relevant wear testing.en_US
dc.description.noteOctober 2013en_US
dc.identifier.urihttp://hdl.handle.net/1993/22055
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectorthopaedicen_US
dc.subjectpin-on-discen_US
dc.subjectwearen_US
dc.subjecttribologyen_US
dc.subjectpolyethyleneen_US
dc.subjecttestingen_US
dc.subjectlubricanten_US
dc.subjectarthroplastyen_US
dc.subjectsynovial fluiden_US
dc.subjectosteoarthritisen_US
dc.subjectperiprostheticen_US
dc.subjectengineeringen_US
dc.titleThe effect of lubricant composition on the wear behaviour of polyethylene for orthopaedic applicationsen_US
dc.typemaster thesisen_US
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