Management of Cardiorenal Metabolic Syndrome in Diabetes Mellitus: A Phytotherapeutic Perspective

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dc.contributor.authorSong, Min Kyong
dc.contributor.authorDavies, Neal M.
dc.contributor.authorRoufogalis, Basil D.
dc.contributor.authorHuang, Tom Hsun-Wei
dc.date.accessioned2014-08-14T06:38:02Z
dc.date.available2014-08-14T06:38:02Z
dc.date.issued2014-4-13
dc.date.updated2014-08-14T06:38:03Z
dc.description.abstractCardiorenal syndrome (CRS) is a complex disease in which the heart and kidney are simultaneously affected and their deleterious declining functions are reinforced in a feedback cycle, with an accelerated progression. Although the coexistence of kidney and heart failure in the same individual carries an extremely bad prognosis, the exact cause of deterioration and the pathophysiological mechanisms underlying the initiation and maintenance of the interaction are complex, multifactorial in nature, and poorly understood. Current therapy includes diuretics, natriuretic hormones, aquaretics (arginine vasopressin antagonists), vasodilators, and inotropes. However, large numbers of patients still develop intractable disease. Moreover, the development of resistance to many standard therapies, such as diuretics and inotropes, has led to an increasing movement toward utilization and development of novel therapies. Herbal and traditional natural medicines may complement or provide an alternative to prevent or delay the progression of CRS. This review provides an analysis of the possible mechanisms and the therapeutic potential of phytotherapeutic medicines for the amelioration of the progression of CRS.
dc.description.versionPeer Reviewed
dc.identifier.citationMin Kyong Song, Neal M. Davies, Basil D. Roufogalis, and Tom Hsun-Wei Huang, “Management of Cardiorenal Metabolic Syndrome in Diabetes Mellitus: A Phytotherapeutic Perspective,” Journal of Diabetes Research, vol. 2014, Article ID 313718, 12 pages, 2014. doi:10.1155/2014/313718
dc.identifier.doihttp://dx.doi.org/10.1155/2014/313718
dc.identifier.urihttp://hdl.handle.net/1993/23757
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2014 Min Kyong Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleManagement of Cardiorenal Metabolic Syndrome in Diabetes Mellitus: A Phytotherapeutic Perspective
dc.typeJournal Article
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