A new diagnostic vestibular evoked response

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Dastgheib, Zeinab A
Lithgow, Brian
Blakley, Brian
Moussavi, Zahra
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Abstract Objective To describe the development of a new clinically applicable method for assessing vestibular function in humans with particular application in Meniere’s disease. Study design Sophisticated signal-processing techniques were applied to data from human subject undergoing tilts stimulating the otolith organs and semicircular canals. The most sensitive representatives of vestibular function were extracted as “features”. Methods After careful consideration of expected response features, Electrovestibulography, a modified electrocochleography, recordings were performed on fourteen Meniere’s patients and sixteen healthy controls undergoing controlled tilts. The data were subjected to multiple signal processing techniques to determine which “features” were most predictive of vestibular responses. Results Linear discriminant analysis and fractal dimension may allow data from a single tilt to be used to adequately characterize the vestibular system. Conclusion Objective, physiologic assessment of vestibular function may become realistic with application of modern signal processing techniques.
Journal of Otolaryngology - Head & Neck Surgery. 2015 Apr 11;44(1):14