Characterization of the mitochondrial genome of Endoconidiophora resinifera explaining the dynamics of mobile elements

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dc.contributor.authorZubaer, Abdullah
dc.contributor.examiningcommitteeCourt, Deborah (Microbiology)en_US
dc.contributor.examiningcommitteeTremblay-Savard, Olivier (Computer Science)en_US
dc.contributor.supervisorHausner, Georg (Microbiology)en_US
dc.date.accessioned2018-09-12T20:39:57Z
dc.date.available2018-09-12T20:39:57Z
dc.date.issued2018en_US
dc.date.submitted2018-08-30T22:04:39Zen
dc.degree.disciplineMicrobiologyen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractFungal mitochondrial genomes are good reservoir of group I and group II introns and intron-encoded proteins (IEPs). Those catalytic introns (ribozymes) and their IEPs have application in biotechnology and have contribution in the mitochondrial genome evolution. We have sequenced mitochondrial genomes of four strains of Endoconidiophora resinifera collected from Europe and North America. Those mitochondrial genomes are among the largest ones of the fungal kingdom having the largest cox1 gene reported so far. The study revealed that the gene or genome size expansion is mainly influenced by the number of intron. An updated model of the mobility mechanism of introns and IEPs was also proposed. An intron landscape was constructed by collecting and aligning nad5 genes from Ascomycota and Basidiomycota to find out the intron homing sites and intron distribution among the fungal species.en_US
dc.description.noteOctober 2018en_US
dc.identifier.urihttp://hdl.handle.net/1993/33338
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectFungal mitochondrial genomeen_US
dc.subjectGroup I intronen_US
dc.subjectnad5 geneen_US
dc.subjectIntron life-cycleen_US
dc.subjectEndoconidiophora resiniferaen_US
dc.titleCharacterization of the mitochondrial genome of Endoconidiophora resinifera explaining the dynamics of mobile elementsen_US
dc.typemaster thesisen_US
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