Transcranial Magnetic Stimulation for Status Epilepticus

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dc.contributor.authorZeiler, F. A.
dc.contributor.authorMatuszczak, M.
dc.contributor.authorTeitelbaum, J.
dc.contributor.authorGillman, L. M.
dc.contributor.authorKazina, C. J.
dc.date.accessioned2015-11-30T15:26:48Z
dc.date.available2015-11-30T15:26:48Z
dc.date.issued2015-11-22
dc.date.updated2015-11-28T07:00:22Z
dc.description.abstractBackground. Our goal was to perform a systematic review on the use of repetitive transcranial magnetic stimulation (rTMS) in the treatment of status epilepticus (SE) and refractory status epilepticus (RSE). Methods. MEDLINE, BIOSIS, EMBASE, Global Health, Healthstar, Scopus, Cochrane Library, the International Clinical Trials Registry Platform, clinicaltrials.gov (inception to August 2015), and gray literature were searched. The strength of evidence was adjudicated using Oxford and GRADE methodology. Results. We identified 11 original articles. Twenty-one patients were described, with 13 adult and 8 pediatric. All studies were retrospective. Seizure reduction/control with rTMS occurred in 15 of the 21 patients (71.4%), with 5 (23.8%) and 10 (47.6%) displaying partial and complete responses, respectively. Seizures recurred after rTMS in 73.3% of the patients who had initially responded. All studies were an Oxford level 4, GRADE D level of evidence. Conclusions. Oxford level 4, GRADE D evidence exists to suggest a potential impact on seizure control with the use of rTMS for FSE and FRSE, though durability of the therapy is short-lived. Routine use of rTMS in this context cannot be recommended at this time. Further prospective study of this intervention is warranted.
dc.description.versionPeer Reviewed
dc.identifier.citationF. A. Zeiler, M. Matuszczak, J. Teitelbaum, L. M. Gillman, and C. J. Kazina, “Transcranial Magnetic Stimulation for Status Epilepticus,” Epilepsy Research and Treatment, vol. 2015, Article ID 678074, 10 pages, 2015. doi:10.1155/2015/678074
dc.identifier.urihttp://dx.doi.org/10.1155/2015/678074
dc.identifier.urihttp://hdl.handle.net/1993/30954
dc.language.rfc3066en
dc.rightsopen accessen_US
dc.rights.holderCopyright © 2015 F. A. Zeiler et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleTranscranial Magnetic Stimulation for Status Epilepticus
dc.typeJournal Article
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