An algorithm for automatic crystal identification in pixelated scintillation detectors using thin plate splines and Gaussian mixture models

dc.contributor.authorSchellenberg, Graham
dc.contributor.examiningcommitteePistorius, Stephen (Physics and Astronomy) LoVetri, Joe (Electrical and Computer Engineering)en_US
dc.contributor.supervisorGoertzen, Andrew (Physics and Astronomy)en_US
dc.date.accessioned2016-01-19T18:02:23Z
dc.date.available2016-01-19T18:02:23Z
dc.date.issued2015
dc.degree.disciplinePhysics and Astronomyen_US
dc.degree.levelMaster of Science (M.Sc.)en_US
dc.description.abstractPositron emission tomography (PET) is a non-invasive imaging technique which utilizes positron-emitting radiopharmaceuticals (PERs) to characterize biological processes in tissues of interest. A PET scanner is usually composed of multiple scintillation crystal detectors placed in a ring so as to capture coincident photons from a position annihilation. These detectors require a crystal lookup table (CLUT) to map the detector response to the crystal of interaction. These CLUTs must be accurate, lest events get mapped to the wrong crystal of interaction degrading the final image quality. This work describes an automated algorithm, for CLUT generation, focused around Gaussian Mixture Models (GMM) with Thin Plate Splines (TPS). The algorithm was tested with flood image data collected from 16 detectors. The method maintained at least 99.8% accuracy across all tests. This method is considerably faster than manual techniques and can be adapted to different detector configurations.en_US
dc.description.noteFebruary 2016en_US
dc.identifier.urihttp://hdl.handle.net/1993/31103
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectDetector, Positron emission tomography, Gaussian mixture models, Thin plate splines, Scintillation crystalsen_US
dc.titleAn algorithm for automatic crystal identification in pixelated scintillation detectors using thin plate splines and Gaussian mixture modelsen_US
dc.typemaster thesisen_US
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