Fecal microbiome, feeding patterns and oxidative stress among preterm infants: an exploratory study
| dc.contributor.author | Morales, Maria | |
| dc.contributor.examiningcommittee | Jones, Peter (Human Nutritional Sciences) Diehl-Jones (Biological Sciences) | en_US |
| dc.contributor.supervisor | Friel, James (Human Nutritional Sciences) | en_US |
| dc.date.accessioned | 2017-01-13T15:06:17Z | |
| dc.date.available | 2017-01-13T15:06:17Z | |
| dc.date.issued | 2016 | |
| dc.degree.discipline | Human Nutritional Sciences | en_US |
| dc.degree.level | Master of Science (M.Sc.) | en_US |
| dc.description.abstract | It is known that the birth process and initial life exposures, such as feeding, may have an important impact on the acquisition of bacterial communities throughout the human body, including the gut. Preterm infants usually have special dietary needs and undergo increased oxidative stress related to intensive care, which can ultimately impair their gastrointestinal microbial colonization and microbial diversity in the bowel. Using molecular techniques, we analyzed the fecal microbiome of 20 preterm infants and tested the association between bacterial communities and feeding type, as well as levels of F2-isoprostanes. We found that feeding influences the fecal microbiome of preterm infants, however more research is needed to clarify the role of human milk fortifiers in this process. We also observed preliminary evidence of an association between microbial composition and oxidative stress, indicating that future studies in this area should be conducted. | en_US |
| dc.description.note | February 2017 | en_US |
| dc.identifier.uri | http://hdl.handle.net/1993/32032 | |
| dc.language.iso | eng | en_US |
| dc.rights | open access | en_US |
| dc.subject | microbiome | en_US |
| dc.subject | oxidative stress | en_US |
| dc.subject | prematurity | en_US |
| dc.title | Fecal microbiome, feeding patterns and oxidative stress among preterm infants: an exploratory study | en_US |
| dc.type | master thesis | en_US |