Effects of fructooligosaccharide alone or in combination with phytase on growth performance, nutrient utilization, immune response and gut development of broiler chickens

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Shang, Yue
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Two experiments were conducted to evaluate the effect of fructooligosaccharide (FOS) supplementation in broiler chickens. In experiment 1, the effect of FOS supplementation and in combination with phytase on growth performance, bone quality and phosphorus utilization was evaluated in broiler chickens fed standard or low calcium (Ca) and phosphorus (P) diets. The phytase supplementation in low Ca and P diets improved growth performance, bone quality and P utilization. The combination of phytase and FOS increased BW gain and P retention. However, supplemental FOS alone had negative effects on bone quality. Experiment 2 investigated the effect of FOS supplementation on growth performance, immune responses, intestinal morphology and ileal microbiota with or without Salmonella Enteritidis lipopolysaccharide (LPS) challenge. Supplemental FOS improved ileal mucosa thickness, modified ileal microbiota, elevated cytokine gene expressions, altered leukocytes composition and increased serum antibody levels in response to LPS challenge. Fructooligosaccharide supplementation may play a protective role on gut development and immunity of broiler chicken.
Fructooligosaccharide, Chicken, Prebiotics, Nutrition, Immune, Microbiota