The Efficacy of Adjunctive Antimicrobial Photodynamic Therapy for Residual Pockets in Previously Surgically Treated Teeth: A Randomized Clinical Trial

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dc.contributor.authorCabrales, Javier
dc.contributor.examiningcommitteeAtout, Reemen_US
dc.contributor.examiningcommitteeBenhamou, Veroniqueen_US
dc.contributor.examiningcommitteePrice, D.en_US
dc.contributor.supervisorCholakis, Anastasia
dc.date.accessioned2022-06-23T15:52:39Z
dc.date.available2022-06-23T15:52:39Z
dc.date.issued2020
dc.date.submitted2022-06-23T15:52:39Zen_US
dc.degree.disciplinePeriodonticsen_US
dc.degree.levelMaster of Dentistry (M.Dent.)en_US
dc.description.abstractPurpose. The aim of this study was to assess the clinical effects of antimicrobial photodynamic therapy (aPDT) delivered as an adjunct to maintenance therapy, specifically in patients with residual pockets at previously surgically treated teeth and compare it with patients receiving mechanical debridement only. Methods and Materials. Twenty-three patients on a regular maintenance schedule who had previously received periodontal surgical care were randomly assigned to receive aPDT or a placebo at their first debridement appointment. The teeth selected had to have at least one site with bleeding on probing and a probing depth of >5mm. One week later, patients received the same treatment according to their group allocation. These teeth were simultaneously reassessed at their three- and six-month maintenance appointments. The primary outcome measure was bleeding on probing (BOP) and secondary outcome measures were plaque index (PI), probing depth (PD), and clinical attachment level (CAL). Results. There were statistically significant (SS) improvements for both groups in mean BOP, PD, and CAL. Individual sites in both groups showed SS improvements in BOP, PD, and CAL as well. When comparing the two groups directly, there was a SS increased mean PD reduction and CAL gain in the adjunctive aPDT treatment over debridement only at 6 months. There were no significant differences between the groups for BOP and PI comparisons. Conclusion. Adjunctive aPDT significantly improves PD and CAL at previously surgically treated teeth in maintenance care, when compared to mechanical debridement alone.en_US
dc.identifier.urihttp://hdl.handle.net/1993/36564
dc.language.isoengen_US
dc.rightsopen accessen_US
dc.subjectRCTen_US
dc.subjectrandomized clinical trialen_US
dc.subjectantimicrobial photodynamic therapyen_US
dc.subjectmechanical debridementen_US
dc.subjectperiodontal surgeryen_US
dc.titleThe Efficacy of Adjunctive Antimicrobial Photodynamic Therapy for Residual Pockets in Previously Surgically Treated Teeth: A Randomized Clinical Trialen_US
dc.typemaster thesisen_US
local.author.affiliationRady Faculty of Health Sciences::Dr. Gerald Niznick College of Dentistry::Department of Dental Diagnostic and Surgical Sciencesen_US
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